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Showing 1 to 1 of 1 for “"inducible hypermutator"”.
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Development and road-testing of an inducible hypermutator strain of Pseudomonas aeruginosa
… (PA), the mutS gene is commonly mutated in hypermutator strains. MutS mutants display an elevated mutation rate (>100-fold, compared with the wild-type (WT)) and are often associated with the acquisition of antibiotic resistance in clinical PA isolates. In the current work, I construct a …