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Showing 1 to 20 of 228 for “"inducer"”.
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Investigation of a Novel Mitophagy Regulatory Pathway and Chemical Inducer
<p>Mitochondria are vital organelles that coordinate cellular energy homeostasis and also have important roles in cell death. Therefore, the removal of damaged or excessive mitochondria through autophagy, a process called mitophagy, is critical for maintaining proper cellular function. Much of the …
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The granulocytic inducer C/EBPalpha inactivates the myeloid master regulator PU.1
Verschiedene Transkriptionsfaktoren spielen eine Rolle in der Entwicklung myeloischer Zellen. PU.1, ein Transkriptionsfaktor aus der ETS-Familie, ist sowohl für die Entwicklung lymphatischer als auch für die Entwicklung myeloischer Zellen von Bedeutung. Der Transkriptions faktor C/EBPalpha, ein an …
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Forced Response Measurements of Cavitation Dynamics in a Rocket Engine Turbopump Inducer
… forced response characterization of cavitating inducers and presents for the first time, damping ratio and natural frequency measurements of surge dynamics using a forced response system identification approach over different cavitation numbers. Cavitation dynamics have been experimentally …
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3-D flow and performance of a tandem-bladed rocket pump inducer
… model of turbulent viscosity for a tandem-bladed inducer in air. The purpose is to understand the 3D flow development through the two blade rows and to compare the results of the calculation 'with experimental data. A literature review tells the story of the inducer from the flat-plate design to …
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Computational study of 3D turbulent air flow in a helical rocket pump inducer
… study of the air flow in a helical rocket pump inducer has been performed using a 3-D elliptic flow procedure including viscous effects. The inlet flow is considered turbulent and fully developed. The geometric, definition of the inducer blade shape and the calculation grid are first presented, …
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C-Rel Is A Transcriptional Target of Mesoderm Inducer In Xenopus Like 1 (Mixl1)
<p>MIXL1, an evolutionarily conserved, paired-type homeobox transcription factor induced by BMP4/TGFb signaling, is a critical regulator of embryonic and adult hematopoiesis. Several lines of evidence implicate MIXL1 in hematopoietic transformation: (i) Aberrant MIXL1 expression is seen in human …
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EARLY GROWTH RESPONSE 1 (EGR1) AS A TUMOR SUPPRESSOR AND APOPTOSIS INDUCER IN RHABDOMYOSARCOMA
EGR1, one of the immediate-early response genes, plays an important role as a mediator for transmitting extracellular stimuli. EGR1 is down regulated in many cancers. Many studies show that it functions as a tumor suppressor gene in a variety of cancers. EGR1 also acts as an oncogene in number of …
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Extracellular Matrix Metalloproteinase Inducer (Emmprin) Regulates Matrix Metalloproteinases in Human and Baboon Uterine Endometrium
Human epithelial endometrial cells secreted a full-length functional form of EMMPRIN that stimulated stromal expression of MMP-1,-2 and -3 but not EMMPRIN. We also found that endogenous stromal cell expression of EMMPRIN was important but not required for MMP stimulation.
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Reduced Order Modeling of a Rocket Engine Turbopump Inducer for Assessment of Pogo Instability
Cavitation in liquid rocket engine turbopump inducers can lead to system instabilities. One form of these flow oscillations is so-called "pogo instability", in which dynamic instability arises from the interaction of vehicle structural dynamics with thrust oscillations of a liquid fueled propulsion …
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Computational study of 3D turbulent flow in a tandem inducer/impeller rocket pump rotor
A computational study of the flow in a tandem inducer/impeller rocket pump has been performed using a 3D elliptic flow program including viscous effects. The axial inducer has four blades and the centrifugal impeller has eight main blades and sixteen splitter blades. The purpose of this thesis is …
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Identification and evaluation of Limosilactobacillus reuteri as an inducer of neonatal IgA and autoimmunity
… reuteri's characteristics as an inducer. Garnering attention for use a probiotic, L. reuteri has many proven health promoting benefits, such as IgA induction, but emerging evidence also links specific strains to autoimmune disease. "Super-induction" of neonatal IgA can be achieved …
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An Inducer of Soybean Phytoalexin and Its Role in the Resistance of Soybeans to Phytophthora Rot
Made available in DSpace on 2014-12-10T23:32:41Z (GMT). No. of bitstreams: 1 7114748.pdf: 591731 bytes, checksum: 5356444849e3dad803a4cd23957a7e19 (MD5) Previous issue date: 1970
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HIF and NF-ĸB Crosstalk: The Role of HIF-1β as an Inducer of the Inflammatory Response
… (TNFSF14) was included in the list of common inducers of NF-kB and HIF. LIGHT was discovered to control HIF induction under normal oxygen levels. In particular, induction of HIF-2α, at mRNA and protein levels, occurred through activation of the non-canonical NF-kB pathway and recruitment of …
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3-D flow and performance of a rocket pump inducer at design and off-design flow rates
The ADP rocket pump inducer was studied computationally using a 3-D Navier-Stokes solver, The Moore Elliptic Flow Program. Design and off-design flow rates were simulated to qualitatively and quantitatively study the effects of flow rate on the flow and performance. Several views of the results …
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The effect of a dietary phase 2 protein inducer on inflammatory parameters in blood and liver of spontaneously hypertensive stroke prone rats
… sprouts, a rich source of phase 2 enzyme inducers such as isothiocyanates, can be incorporated into the diet to increase phase 2 enzymes. The hypothesis of this study is that, the dietary intake of dried broccoli sprouts, by inducing liver phase 2 enzymes, will decrease oxidative stress …
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A body force model for cavitating inducers in rocket engine turbopumps
… rocket engine turbopumps utilize cavitating inducers to meet mass and volume requirements. Rotating cavitation and higher order cavitation instabilities have frequently been observed during inducer testing and operation and can cause severe asymmetric loading on the inducer blades and shaft, …
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Characterization of cavitation instabilities in rocket engine turbopump inducers
… around the periphery of rocket engine turbopump inducers, rotating cavitation is the primary cavitation instability considered in this thesis. A recently developed hypothesis for rotating cavitation onset is assessed through novel experimental analysis and a previously developed body force …
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