Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 13 of 13 for “"individual participant data"”.
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The Use of Individual Participant Data (IPD) for Examining Heterogeneity in Meta-analysis of Observational Studies: An Application to Biomechanical Workplace Risk Factors and Low Back Pain
… is particularly important when combining data from observational studies. This thesis presents the results of a study that examines the relative ability of individual participant data (IPD) meta-analysis (which was considered a “gold standard”) and traditional aggregate data (AD) …
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Attachment and Trauma: A Historical and Empirical Study of the Meaning of Unresolved Loss and Abuse in the Adult Attachment Interview
… about child abuse. In the second study, individual participant data were used from 1,009 parent-child dyads across 13 studies. Interviewees with or without unresolved loss/abuse were differentiated by subsets of commonly occurring indicators of unresolved loss/abuse. Predictive models …
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Epidemiological studies of whole blood donation in the UK: Donor safety and retention
… collection and adverse events; (ii) identify individual and collection site characteristics associated with return behaviour; (iii) characterise in detail the cross-sectional associations of the three optimal indices for defining iron deficiency (i.e., haemoglobin, ferritin, and soluble …
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Modelling non-linear exposure-disease relationships in a large individual participant meta-analysis allowing for the effects of exposure measurement error
This thesis was motivated by data from the Emerging Risk Factors Collaboration (ERFC), a large individual participant data (IPD) meta-analysis of risk factors for coronary heart disease(CHD). Cardiovascular disease is the largest cause of death in almost all countries in the world, therefore it is …
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Late stillbirth: the contribution of maternal sleep practices and maternal views
… We pooled the eligible studies into an individual participant data metaanalysis, concluding that supine going-to-sleep position should be considered a contributing factor for late stillbirth in all pregnancies. We also hypothesised that supine going-to-sleep position may interact with …
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Evidence Synthesis and targeting further research for adherence and stratification in health economic evaluations
… are often not modelled due to a lack of good data. A case study of treatment for patients with sleep apnoea is used to illustrate these methods and techniques. Value of Information measures can help prioritise where to focus further research and estimate the expected benefits from a study of …
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Transfer of automatic skills: the role of automaticity in skill acquisition and transfer
… design. The study has a particular emphasis on individual differences, and thus individual participant data are explored to determine the pervasiveness of trends observed in the group data. In experiment one it was found that experimental design might play a role in the acquisition and …
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Management of late term pregnancy
… mortality and morbidity. Paper II was a one-step individual participant data (IPD) meta-analysis (n=5 161 for aggregate data and 4 561 for IPD) and included trials comparing IOL in women with a low-risk singleton pregnancy at 41 GW with EM until 42 GW. Primary outcome was a composite of perinatal …
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Investigating the Role of Eating Behaviour Traits in Behavioural Weight Management Interventions from a Precision Treatment Perspective
… treatments aim to improve outcomes by matching individuals to different intervention types based on their personal characteristics, such as their Eating Behaviour Traits (EBTs). EBTs are defined as tendencies determining an individual’s food intake and have previously been linked to the …
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Meat consumption and type 2 diabetes: investigating heterogeneity and potential causal mechanisms
… worldwide, imposing enormous burdens on affected individuals and their families, healthcare systems and societies. Healthy diets play a crucial role in preventing T2D and meat has been reported to be associated with an increased risk of T2D. However, it is unclear whether different types of meat …
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Efficacy of oral corticosteroids for preschool wheeze
… health professionals (HPs) and patients into an individual participant data (IPD) analysis. METHODS: This PhD project comprises four complementary phases. In Phase One, I conducted a global systematic review and meta-analysis of the literature published between 1994 and 2020 in eight databases. …
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Examining inequalities in behavioural weight management interventions
Interventions designed to support individuals to change their health behaviours, such as behavioural weight management interventions, typically require a high amount of personal agency (such as time, money, and education) to be effective. As a result, these interventions may benefit advantaged …
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The evaluation of different strategies to improve the diagnosis of tuberculosis in people living with HIV in resource-limited settings
… Methods We conducted a systematic review and individual participant data (IPD) meta-analysis. We updated a search of PubMed (MEDLINE), Embase, Cochrane Library, and conference 2 abstracts for publications from Jan 1, 2011, to March 12, 2018, done in a previous systematic review to include the …