Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"indian hedgehog"”.
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Lineage specification of ovarian theca cells requires multi-cellular interactions via oocyte and granulosa cells
… birth, in response to paracrine signals Desert hedgehog (Dhh) and Indian hedgehog (Ihh) from granulosa cells. Ovaries lacking Dhh/Ihh exhibited a loss of theca layer, blunted steroid production, arrested folliculogenesis, and failure to form corpora lutea. Production of Dhh/Ihh in granulosa …
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MOLECULAR CHARACTERIZATION OF THE PUTATIVE NUCLEOTIDE- BINDING AND HYDROLYZING ACTIVITIES OF THE ELLIS VAN CREVELD (EVC) PROTEIN
… assembly positively regulates the Sonic and Indian hedgehog signaling pathways by promoting downstream processes after activation of the smoothened receptor (Smo), by the hedgehog proteins. Bioinformatic analysis revealed the presence of several structural motifs in EVC sequences including …
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Ihh Signaling and Muscle Forces are Required for Enthesis Development
… Using a murine reporter of active Indian hedgehog (Ihh) signaling, we identified a population of cells present early in development that populate the mature enthesis. Lineage tracing analyses indicated that this cell population remained at the mature enthesis while down-regulating …
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Dissecting the Role of Hedgehog Signaling in Tumor-associated Macrophages and Immunosuppression in the Tumor Microenvironment
… the tumor microenvironment (TME).</p><p>The hedgehog (Hh) signaling pathway is one of the most important signaling pathways in cancer. Its aberrant activation within cancer cells can lead to increased proliferation and metastasis. Hh ligands, including sonic hedgehog (Shh), desert hedgehog …
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Molecular mechanisms regulating implantation
… via Leukaemia Inhibitory Factor (LIF) and Indian Hedgehog (IHH). The second part of this study investigates the role of signal transducer and activator of transcription 3 (STAT3) in the uterine epithelial cells during implantation. STAT3 is activated downstream of LIF, an E target gene, in …