Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"in-vitro diagnostic"”.
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Engineering non-immunoglobulin binding proteins for in vitro diagnostic Tests
In 2016, nearly 5.5 million deaths were attributed to infectious and parasitic diseases. Although many of these diseases are preventable and treatable, resource-constrained regions often lack access to rapid and accurate diagnostic tests to appropriately diagnose and treat these diseases. In order …
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Development of UK legislation Guidance for Research Medical and In Vitro Diagnostic Devices
… and manufacture of medical devices and in vitro diagnostic devices in the United Kingdom (UK) and the European Union (EU). Organisations working in this field can demonstrate their regulatory compliance to this legislation by being accredited to BS EN ISO 13485 – BS EN ISO 13485:2016 …
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Economic potential for clinically significant in vitro diagnostics
In recent years, significant advances have been made in the realm of in vitro diagnostics with the development of novel tests which are able to meaningfully impact the course of a patients' disease management. This transformation has strained the traditional in vitro diagnostic business model and …
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Establishment of checklist of design for safety (DfS), life-cycle analysis (LCA) and design for manufacturing (DFM) for IVD medical device based on IEC 60601
By 2030, medical industries is projected to grow exponentially, progressive to more sustainable policies and better performance towards achieving healthcare Sustainable Development Goals (SDGs). Designing the uprising star of In-Vitro Diagnostic (IVD) device casing is choose as a case study in this …
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Development and Application of Reference Measurement Procedures for C-peptide and Insulin in Human Serum
The final goal of the research presented in this dissertation is to solve the current problems existing in the clinical laboratory derived from the lack of comparability of results when different methodologies are used. These may be caused by the lack of standardization or the presence of …
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Molecular and Biofunctional Modification of Conformal POEGMA Bottlebrush Coatings and Applications Toward In Vitro Diagnostics
<p>In vitro diagnostic assays (IVDs) play a crucial role in modern biomedical research and clinical decision-making. The overall performance and cost of IVDs depends considerably on the quality of the assay surface being used and the steps/reagents required to complete the assay. Synthetic …
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Requirements for Covid-19 swabbing
… pandemic has warranted the urgent need to test infected individuals to prevent further virus spread. This has led to establishing Covid-19 testing centres within different areas in the community to promote early detection and isolation of cases. In the effort to ensure a safe and efficient …
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Fluorinated Nanoparticles: A Novel Technology Platform for Multimodal Biomedical Imaging Applications
Fluorinated compounds have many applications in medicine, including oxygen transport, drug delivery vehicles, and contrast agents in medicine due to fluorine's unique chemical and nuclear properties. Fluorinated compounds have been used in microbubble contrast agents for ultrasound imaging, …
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Entwicklung einer parallelen Mehrkomponentenanalyse von Antigen-Antikörper-Reaktionen in der Dopinganalyse
Weltweit streben Anti-Doping Institute danach jene Sportler zu überführen, welche sich unerlaubter Mittel oder Methoden bedienen. Die hierfür notwendigen Testsysteme werden kontinuierlich weiterentwickelt und neue Methoden aufgrund neuer Wirkstoffe der Pharmaindustrie etabliert. Gegenstand dieser …
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Lanthanides and quantum dots : time-resolved laser spectroscopy of biochemical Förster Resonance Energy Transfer (FRET) systems
… for biochemical applications such as DNA sequencing, intracellular protein-protein interactions, molecular binding studies, in vitro diagnostics and many others. For qualitative and quantitative analysis, FRET systems are usually assembled through molecular recognition of biomolecules conjugated …
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Fully Integrated Modular and Mixed-Scale Systems for Processing the Molecular Cargo of Liquid Biopsy Markers
Precision medicine is the concept of delivering the right treatment, to the right patient, at the right time. However, accessibility to precision medicine is still a major challenge. The field of distributive medicine aims to rectify this by creating biomedical solutions that increase access to …
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Advances in molecular-based diagnostics and biomolecular interaction screening using silicon photonic microring resonators
Personalized medicine promises that improved information leads to improved treatments, that each individual has unique genetic, clinical, and environmental factors which are ultimately responsible for the distinct molecular mutations which drive disease as well as variation in treatment efficacy. …
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Development of silicon photonic microring resonator biosensors for multiplexed cytokine assays and in vitro diagnostics
In order to guide critical care therapies that are personalized to a patient’s unique disease state, a diagnostic or theranostic medical device must quickly provide a detailed biomolecular understanding of disease onset and progression. This detailed molecular understanding of cellular processes …
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Advanced modeling and design optimization for biomedical industry seeking enhanced reliability and cost efficiency
… è presente nell'allegato / the abstract is in the attachment
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Development and evaluation of a new biochip Nucleic Acid Test (NAT) multi-target for cervical cancer screening
Cervical cancer is the fourth most common cancer in women and the cytological screening represents the most diffuse method of prevention. Human papillomavirus (HPV) is an established essential etiological factor for this cancer. Persistence of HPV infection, particularly by those belonging to the …