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Showing 1 to 12 of 12 for “"in vivo dosimetry"”.
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In Vivo Dosimetry Using Plastic Scintillation Detectors For External Beam Radiation Therapy
<p><em>In vivo</em> dosimetry, the direct measurement of dose delivered to patients during radiation therapy, has significant potential in ensuring safe and effective treatment in radiation therapy. It can serve as point-of-delivery, patient specific quality assurance and direct verification of …
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Characterization of p-type silicon semiconductor detectors for use in in vivo dosimetry
The response of a p-type diode detector for use in patient dose monitoring in photon and electron fields was evaluated for a number of commonly-encountered clinical parameters. Effects of energy, field size, source-to-surface distance, presence of beam modifiers, beam orientation, and temperature …
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The use of thermoluminescent dosimeters for In-vivo dosimetry in a fast neutron therapy beam
Thermoluminescent detectors (TLD-700) have been investigated for absorbed dose measurements in a p(66)/Be neutron therapy beam at the National Accelerator Centre. Chips were selected based on their reproducibility and chip individual neutron calibration factors were derived. The dose non-linearity …
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Dose intercomparisons between computer planning, in-vivo and phantom measurements for Iridium-192 HDR Brachytherapy
During gynaecological high-dose rate (HDR) intracavitary brachytherapy (ICBT), invivo dosimetry is done to monitor the dose received by the bladder and rectum. This study was aimed at validating the need to do in-vivo dosimetry during ICBT. Thirty patients were recruited to participate in the …
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Targeted 177 Lu antisense radiotherapy of B-cell non-Hodgkin's lymphoma
… lymphoma/leukemia-2 (bcl-2) proto-oncogene in non-Hodgkin's lymphoma (NHL) is a dominant inhibitor of apoptosis. The research goal was to develop a [superscript 177]Lu-labeled bcl-2 antisense peptide nucleic acid (PNA)-peptide conjugate designed for dual modality NHL therapy, consisting of a …
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Design, Fabrication, and Validation of 3D Printed, Patient-Specific Compensators For Postmastectomy Radiation Therapy
<p>The purpose of this study was to use 3D printed, patient-specific tissue compensators to overcome the 3D planning limitations for postmastectomy radiation therapy (PMRT). Tissue compensators can be used to reduce dose heterogeneity, hot and cold spots at field junctions, and treatment …
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Point-based Ionizing Radiation Dosimetry Using Radiochromic Materials and a Fibreoptic Readout System
Real-time feedback of absorbed dose at a point within a patient can help with radiological quality assurance and innovation. Two radiochromic materials from GafChromic MD-55 and EBT films have been investigated for applicability in real-time in vivo dosimetry of ionizing radiation. Both films were …
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Real-Time Radiation Detection within the Gastrointestinal Tract
The risk of a radiation emergency is becoming more prevalent as the misuse of nuclear facilities or technologies by terrorists or rogue nation-states continues to increase. A radiation emergency could cause instantaneous and sustained large releases of penetrating radiation, which would result in …
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Progress on 2D-MoS2: development of a scalable fabrication method and demonstration of an X-ray detector
… dichalcogenides (TMDCs) aroused significant interest in the last years as semiconductor materials for application in the field of electronics, due to their tunable bandgap, good carrier mobility, and strong light absorption. Among TMDCs, two-dimensional molybdenum disulfide (2D-MoS2) has been …
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Range Adaptive Proton Therapy For Prostate Cancer
… distal falloff of a proton beam allows for sparing of normal tissues distal to the target. However proton beams that aim directly towards critical structures are avoided due to concerns of range uncertainties, such as CT number conversion and anatomy variations. We propose to eliminate range …
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An Implantable Mosfet Dosimeter Modified to Act As A Fiducial Marker
In external beam radiation therapy, it is imperative that the prescribed dose is administered to the correct location and in the correct amount. Though several ex vivo methods of quality assurance are currently employed to achieve this goal, verifying that the correct dose is received within the …
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A Computerized Image Analysis System for the SSNTD CR-39
Made available in DSpace on 2017-07-06T18:42:31Z (GMT). No. of bitstreams: 3 Briggs_Stephen_J_MS.pdf: 33415726 bytes, checksum: de5e59dbbe863b620fe21c74e9fd9fb8 (MD5) Briggs_Stephen_J_MS_ABS.pdf: 957747 bytes, checksum: 4750bd0e85e1075f626da29472a3bef7 (MD5) license.txt: 4813 bytes, checksum: …