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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 446 for “"in vivo and in vitro"”.
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Plasmodium Gallinaceum in Vivo and in Vitro
The findings presented in this dissertation provide a more solid foundation for the comparison of avian malaria with falciparum malaria, and strengthen the rationale upon which to base development of attenuated live sporozoite vaccines for falciparum malaria.
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Toxicopathology of microcystin-LR in vivo and in vitro
Microcystin-LR (MCLR), produced by the blue-green alga Microcystis aeruginosa, causes death of livestock and is a public health hazard. The mechanism of MCLR toxicity was investigated using the rat. Changes in serum chemistry parameters and morphology caused by MCLR were characterized in vivo and …
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Studies on Chloroplast Protein Synthesis In Vivo and In Vitro
<p>Protein synthesis in the Chlamydomonas reinhardtii chloroplast was investigated by in vivo and in vitro approaches. The site of synthesis of chloroplast proteins was examined to determine how many proteins were synthesized inside the chloroplast. Cells were labeled in vivo with …
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Aspects of in Vivo and in Vitro Transcription in Yeast
… of transcription by yeast RNA polymerase II and the yeast mitochondrial RNA polymerase both in vivo (in plasmid containing cells) and in vitro (in cell-free protein extracts). A complete in vivo transcription map of the yeast centromere plasmid YCp19 was determined, and the transcripts from …
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Bacteriophage-T4 Ribonucleic Acid Synthesis, in Vivo and in Vitro
Made available in DSpace on 2014-12-09T17:36:01Z (GMT). No. of bitstreams: 1 6812099.pdf: 2113634 bytes, checksum: 162fbf0961ffeacd224e6a9cd0335f86 (MD5) Previous issue date: 1968
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Engineering programmable nucleases for in vivo and in vitro applications
… biotechnology development. Enzymes such as zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), clustered regularly interspaced short palindromic repeats (CRISPR) associated nucleases, and Argonaute nucleases (Ago) have revolutionized genome engineering by …
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In-Vivo and In-Vitro Cholesterol Removal by Lactobacilli and Bifidobacteria
Four strains of Lactobacillus acidophilus, eleven strains of L. casei and five strains of Bifidobacterium were studied for their acid and bile tolerance. Possible mechanisms of cholesterol removal were also examined. All strains showed varying levels of tolerance at pH 2.0 for two hours. L. …
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Genetic and Epigenetic Interactions in in vivo and in vitro Reprogramming
<p>In cancer pathogenesis and induced pluripotent stem: iPS) cell production, an essential step for reprogramming is acquisition of self-renewal. In hematopoietic cells, HOX genes are partially responsible for self-renewal, and HOX gene dysregulation commonly occurs in acute myeloid leukemia: AML). …
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In vivo and in vitro studies of immunodeficiency in Ataxia-telangiectasia
… neurodegenerative disorder caused by mutations in the ATM gene which has a central role in the cellular response to DNA double strand breaks, cell cycle checkpoint control and initiation of the intrinsic pathway of apoptosis. Ataxiatelangiectasia is classified as an immunodeficient disorder with …
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Metabolism of Biuret by Ruminants: In Vivo and In Vitro Studies
Made available in DSpace on 2014-12-10T22:30:27Z (GMT). No. of bitstreams: 1 7317448.pdf: 3113238 bytes, checksum: cf0d8ad5c00a2d9261ae64b9c7105039 (MD5) Previous issue date: 1972
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Transcriptional Characterisation of Human Musculoskeletal Development in vivo and in vitro
… range of diseases throughout life, often affecting young, economically active people. These diseases are the leading cause of morbidity worldwide. Despite this, this organ system is rarely the focus of large scientific initiatives. For example, it was absent from the original Human Cell Atlas …
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Mouse cortical cholinergic neurons: Ontogeny of phenotypes in vivo and in vitro.
The development of cholinergic neurons in mouse frontal cortex was studied both in vivo and in vitro by immunocytochemistry with an antibody to choline acetyltransferase (ChAT), the enzyme responsible for acetylcholine synthesis. While cortical cholinergic neurons have previously been characterized …
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In vivo and in vitro guidance of developing neurons by mechanical cues
During nervous system development, growing axons navigate towards their targets using signals from their environment. These signals may be biochemical or mechanical in nature; however, the role of mechanical cues in axon pathfinding in vivo, and the spatiotemporal dynamics of embryonic brain …
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In vivo and in vitro regulation of plasminogen activator inhibitor type-1
The human leukaemic cell line, K562 can be induced to differentiate along the megakaryoblastic pathway by the addition of phorbol myristate acetate and, during this process, the cells switch from producing a mixture of active tissue plasminogen activator (t-PA) and urokinase (u-PA) to producing …
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Composition and in vivo and in vitro digestibility of cattle fecal waste
… digestion trials were conducted with six yearling steers to study apparent digestibility of fecal waste from steers fed a ground, high roughage finishing ration. In the first trial steers were fed a basal ration containing approximately 50% roughage. The ration contained 14.3% crude protein and …
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Effects of fatty acids on inflammatory markers studied in vivo and in vitro
Inflammation involves interactions amongst many different cell types as a defense mechanism of the body. Inflammation is also involved in cardiovascular disease (CVD). The role of long chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs) in modulating the inflammatory response has been proposed. …
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The role of plant extracts on islet function in vivo and in vitro
… 2 diabetes mellitus (T2DM) for many centuries, and offer the potential of cheap and readily available alternatives to conventional pharmaceuticals in developing countries. Extracts of Gymnema sylvestre (GS) and Costus pictus (CP) are reported to have antidiabetic activity in vivo. The exact …
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