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Showing 1 to 2 of 2 for “"in situ cryo-electron tomography"”.
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Investigating the cytoskeleton and microtubule-based transport with in situ cryo-electron tomography
The cytoskeleton is composed of microtubules, actin, and intermediate filaments, which function both as a cellular scaffold and as tracks for motor proteins that drive intracellular transport. Cytoplasmic dynein, in combination with dynactin and activating adaptors, is a microtubule-based motor …
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ADVANCING IN SITU CRYO-ET TO THE NEXT DIMENSION: TOMOGRAPHY ON 3D ORGANOIDS
Interpreting how molecular organization supports cell and tissue function remains a central challenge in biology. In situ cryo-electron tomography (cryo-ET) can help to address this challenge by providing high-resolution, three-dimensional visualization of macromolecules in near-native, minimally …