Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"imprinting control region (ICR)"”.
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Oct4 and Sox2 regulate methylation at the Igf2/H19 imprinting control region
… depends on parental-specific methylation of an imprinting control region (ICR). Although CTCF sites maintain the absence of DNA methylation on maternal ICRs after fertilization, some Beckwith-Wiedemann patients showed maternal ICR methylation that correlated with mutations in one of the pair of …
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Regulation of the Kcnq1ot1 Imprinting Domain in Mouse
Genomic imprinting is an epigenetic mechanism that controls gene expression based on parental-origin of an allele. The Kcnq1ot1 imprinting cluster consists of an imprinting control region (ICR), the Kcnq1ot1 ncRNA, and maternally expressed protein-coding genes. Truncation of the Kcnq1ot1 ncRNA or …
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Imprinted Gene Expression and Phenotype of Bovine Concepti with Bos taurus and Bos indicus Genetics
… imprinted genes were subject to developmental control of gene expression with the transcript abundance being downregulated in postnatal tissues. We identified IGF2 promoter-specific transcripts and the bovine orthologue of human P0 promoter, and found a developmental shift in tissue specificity …