Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"immunomodulatory protein"”.
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Development and Characterization of A Recombinant Orf Virus Vector Expressing the Spike Protein of Porcine Epidemic Diarrhea Virus
… the virus entry sites. ORFV has evolved several immunomodulatory proteins (IMPs) that evade and/or modulate host immune responses to infection and contribute to virus virulence and disease pathogenesis. Given biological properties and unique immunomodula tor y properties, ORFV has gained …
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Analyzing Extracellular Vesicles for Disease Monitoring in Metastatic Colorectal Cancer Patients
… cell-to-cell communication and carry surface proteins and cell-specific cargos of nucleic acids. For this reason, we aimed to characterize ribonucleic acid (RNA) cargoes and surface proteins on EVs disseminated from CRC cancer cells to longitudinally monitor mCRC patients and identify immune …
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Characterization of the anti-type I interferon effects of the cellular flice-like inhibitory protein (CFLIP)
The cellular FLICE-like inhibitory protein (cFLIP) is well known as a major immunomodulatory protein. Various works have described its role in major cellular pathways such as apoptosis, autophagy, necroptosis, NF-KB regulation and more recently, modulation of interferon responses. Interferon alpha …
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Cytokine-bearing Influenza Vaccine: Adjuvant Potential of Membrane-bound Immunomodulators
… the properties of individual cytokines and other immunomodulatory proteins to create a more immunogenic vaccine. Here we report methodologies for the construction of membrane-bound cytokine fusion constructs in which our cytokine of interest (mouse GM-CSF, mouse IL-2, mouse IL-4) was fused to the …