Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 721 for “"immunological"”.
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On Immunological Imprinting
Immunological memory is considered the hallmark of the adaptive immune system, where primary exposure to an antigen establishes a population of memory cells capable of responding to future encounters to the same antigen with increased speed and magnitude. For rapidly mutating respiratory pathogens …
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Vaccination and immunological memory
Human subjects maintain long-term immunological memory against infective organisms but the mechanism is unclear. CD4+ T helper memory cells (Thmem) are pivotal in controlling humoral and cellular responses, therefore their longevity and response to vaccination are critical for maintenance of …
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Immunological aspects of thyrotoxicosis
306 leaves
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Immunological investigations into synaptic plasticity
Antibody technology was applied to the study of synaptic plasticity resulting from passive avoidance training in the chick and long-term potentiation in the rat. These studies fell into three categories: 1) the disruption of memory for a one-trial passive avoidance task by intracranial injection of …
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Immunological analysis of pericardial tuberculosis
Pericardial tuberculosis (TB) offers a relevant human model to study TB at the site of disease and to determine the effect of HIV-1 infection. 96 Patients with pericardial TB were recruited into this study, 68 of whom were HIV-1 infected. Where clinically indicated, pericardiocentesis was performed …
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Immunological synapse arrays : patterned protein surfaces that modulate immunological synapse structure formation in T cells
… at the T cell-APC interface known as the immunological synapse (IS). It remains unresolved whether the unique physical structure of the synapse itself impacts the functional response of T cells, independent of the quantity and quality of ligands encountered by the T cell. As a first step …
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Immunological control of toxoplasma gondii infection
Prevalent worldwide, the protozoan parasite, Toxoplasma gondii, is an important cause of spontaneous abortion, ocular disease, mental retardation and encephalitis. Currently there are no human vaccines available. The first major aim of this study was to test potential HLA restricted peptide …
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Immunological mechanisms controlling chronic inflammatory diseases
Autoimmune diseases (AID) are chronic inflammatory diseases (CID) mediated by self-reactive T and B cells and are generally the results of the breakdown of T cell tolerance to self-antigen and failure of peripheral regulatory mechanisms. In this thesis I studied different mechanisms controlling the …
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Immunological markers in hairy-cell leukaemia
… Chapter 1 presents a brief introduction on immunological markers. Chapter 2 describes the discovery of a previously unrecognised marker in hairy-cell leukaemia (HCL), a receptor for IgM. The rosette method used to reveal this receptor, and the conditions affecting rosette formation are …
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The Immunological Behavior of Baby Pigs
Made available in DSpace on 2014-12-05T22:04:02Z (GMT). No. of bitstreams: 1 6206170.pdf: 8206013 bytes, checksum: 0ac9e7ecb4a11880ce314ca00b60337d (MD5) Previous issue date: 1962
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Heat shock proteins as immunological carriers
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1998.
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Determining and characterizing immunological self/non-self
… species is stored in a library and defines its "immunological self". Using the libraries, organisms can be compared to determine the levels of peptide overlap. The observed levels of overlap can also be compared with levels which can be expected "at random" and statistical conclusions drawn.A …
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Human Papillomavirus vaccination: Immunological and epidemiological studies
This thesis has evaluated the immunological- and epidemiological aspects of human papillomavirus transmission dynamics and its effect on circumcision. Effective prophylactic vaccines are based on type-specific neutralizing antibodies. A major neutralizing epitope is defined by the monoclonal …
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Biochemical and immunological investigations into cystic fibrosis
In an attempt to produce a quantitative biochemical assay which would assist in the detection of individuals heterozygous and homozygous for the cystic fibrosis (CF) gene, two general approaches were adopted. In the first, attempts were made to produce an antiserum specific for the cystic fibrosis …
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Immunological responses following surgery in ulcerative colitis
… like ANCA, are also found in UC, suggesting immunological similarities with systemic vasculitis. Perhaps, UC represents a gut limited vasculitis. Persistance of ANCA, AECA, anti-EPI and antitropomyosin antibodies in the sera, several years following total colectomy, suggests that …
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A cytochemical and immunological study of tumour cells
Initial tumour growth was found to be exponential following intraperitoneal inoculation of 5 x 106 Ehrlich ascites tumour cells into male BALB/c mice. After three days of this pattern the rate of growth became noticeably retarded and after 12 days a plateau phase ensued. The reduced growth rate was …
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Outcome selection in longitudinal analysis of immunological data
Immunological research often compares subgroups defined by exposure variables known (or hypothesised) to influence continuous immune responses. Many immune outcomes are measured over time, often in a small number of patients. Effective outcome selection ensures that research focuses on immune …
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Enzyme Linked Immunological Studies of Cholinesterases in Human Blood
… erythrocyte AChE activity (CV=7%). Reliable immunological quantitation of this enzyme (CV=7%) was achieved using monoclonal antisera to AChE (AE-1 and AE-2) in a fluid phase homogeneous enzyme-linked antiglobulin test (ELAT). AChE activity and antigen levels were similar for both adult male …
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