Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 91 for “"immunohistochemical staining"”.
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Expression of X-linked Inhibitor of Apoptosis Protein in Neoplastic Thyroid Disorder
… Expression of XIAP was evaluated with immunohistochemical staining using monoclonal anti-XIAP in 164 specimens of conventional papillary thyroid carcinoma (PTC) and 53 specimens of other malignant or benign thyroid tumors. The presence of the BRAFV600E mutation was evaluated using PCR …
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비인강암 환자에서 Excision Repair Cross-Complementation Group1 단백의 과발현이 예후에 미치는 영향
… 3 1. Chemoradiotherapy 3 2. Evaluation 4 3. Immunohistochemical staining for ERCC1, TS and Bax 4 4. Statistical analysis 5 Ⅲ. RESULTS 7 1. Patients characteristics 7 2. Treatment response 8 3. Association of expression of drug resistance-related proteins with clinicopathologic charecteristics …
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Molecular Signatures of gastric cancer: An integrated approach to molecular cytogenetics, whole genome copy number and transcriptome profiles
… supervised hierarchical clustering of 18q genes. Immunohistochemical staining of 18q proteins, Serpin B8 and CD226 antigen, showed overexpression in breakapart-positive primary gastric cancers. Other molecular signatures from whole genome copy number, mRNA and miRNA profiles are described.
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Identification of Apoptotic Regulators in the Cervix of Pregnant Mice in Association with Cervical Softening
… ratio was increase latter stage of pregnancy. Immunohistochemical staining shows that Bax, Caspase-3, Caspase-6 significantly detected in the latter stage of pregnancy. Stromal disorientations associated with apoptosis were identified. In conclusion, apoptosis associated with ripening is …
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A Multifaceted Approach to Study Salmonella Typhimurium Pathogenesis
… S. typhimurium in the aorta by using an indirect immunohistochemical staining procedure which shows a direct correlation between the presence of bacteria and neutrophils in the infected tissue.
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Expression of Survivin : Possible Predictor of Local Recurrence after Curative Resection for Rectal Cancer
… recurrence with rectal cancer, staged Ⅱ and Ⅲ. Immunohistochemical staining for p53, bcl-2, survivin and cleaved caspase-3 were performed on paraffin-embedded tissue sample of 46 rectal cancer. By clinicopathological data, risk factors for local recurrence were positive nodes (45% vs 69.6%, …
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CD146 expression in early and late onset pre-eclampsia : is there a difference?
… the difference in expression of CD146 immunohistochemical staining on intermediate trophoblast in early and late onset pre-eclampsia placentas as well as comparing this expression to gestational age matched control placentas. Study Design: Retrospective case series of 100 placentas: 25 …
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The Expression of Syndecan-1 is Related to the Risk of Endometrial Hyperplasia Progressing to Endometrial Carcinoma
… malignancies. The current study describes the immunohistochemical study of syndecan-1 expression in normal, hyperplastic, and malignant endometrial tissues for evaluation of application as a parameter of cancer progression in patients with endometrial hyperplasia. Methods: Immunohistochemical …
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Expression and Clinical Significance of the N-myc downstream regulated gene-1 in Hypopharyngeal Cancer
… (SCC). Materials and methods. We performed immunohistochemical staining of 56 specimens each of normal mucosa and SCC of the hypopharynx with Ndrg-1 antibodies. For reverse transcriptase polymerase chain reaction (RT-PCR) and Western blotting, fresh normal and cancer tissue from the …
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Melanocyte proliferation in wounded skin in vitro: a histological and immunohistochemical analysis
… contributed to the growth of the tongues, immunohistochemical staining using the proliferation marker, Ki67, was used. Results show that after an initial lag phase, with no detectable cell proliferation at the wound edges, dividing keratinocytes were seen at day two post-wounding. The …
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A light and electron microscope investigation of the host-parasite relationship in the brains of mice with congenital toxoplasmosis.
… enclosed within the host cell membranes. Immunohistochemical staining confirmed that this layer contained neurofilament protein. Interior to this layer was a much convoluted parasitophorous vacuole membrane; exterior was the host cell membrane. In most cases, synaptic plates were noted on …
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A Novel Quantitative Mechanical Test of Atherosclerotic Plaque Stability
… MMP12 DKO mice was not significantly different. Immunohistochemical staining showed that macrophage content of aortic plaques is neither significantly correlated with G values nor significantly different between these two strains of mice. Overall, our results suggest that plaques adhere more …
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The Effects of Tamoxifen on Mammary Development in Prepubertal Heifers
… middle and outer regions) were processed for immunohistochemical staining for Estrogen Receptor α and Progesterone Receptor, myoepithelial cells, and label retaining cells. Overall, the proportion of neither ER nor PR labeled cells was impacted by TAM treatment. However, imaging analysis …
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Tmprss2-Erg Regulation Of Androgen Biosynthetic Enzyme Expression, Dht Synthesis, And Androgen Receptor Activation In Prostate Cancer
… 5a-Androstanedione, a DHT precursor metabolite. Immunohistochemical staining revealed that ERG was co-expressed with AKR1C3 in PCa tissue samples. These data suggest that AKR1C3 catalyzes the biochemical reduction of 5a-Androstanedione to DHT in PCa cells, and that ERG regulates this step through …
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Neuronal PAS Domain 1 Protein and Its Hypothetical Relationship to Autism
… hypothalamus and superior colliculus. Subsequent immunohistochemical staining assays employing antibodies to NPAS1 revealed an expression pattern largely restricted to inhibitory neurons in the aforementioned brain regions, as well as localized expression in the subgranular region of the dentate …
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Characterising human lung tissue for biomarkers of EMT-fibrosis and functional steroid receptor components in chronic obstructive pulmonary disease (COPD) patients and control subjects
… of COPD patients and control subjects using immunohistochemical staining. The result obtained describes that S100A4 (EMT marker) was more highly expressed in active smokers (non-smoker and ex-smoker, versus current, p<0.0001). TTC5 expression was higher in both ex-smokers and current smokers …
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The role of EGFR, HER 2-4, heregulin and downstream signalling in prostate adenocarcinoma
… proliferation or apoptosis. Patients and Methods Immunohistochemical staining for HRG, KI67 (proliferation), TUNEL (apoptosis) was performed on pilot study specimens. Further IHC for EGFR, HER2, HER3, HER4, HRG, KI67 and TUNEL was performed on HSPC tissue microarrays. Correlations between target …
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Study on the Neuroprotective Effects of Ethyl pyurvate in MPTP-induced Mouse PD Models
… in the MPTP-treated substantia nigra. Additional immunohistochemical staining also showed that MPTP induced glial cell line-derived neurotrophic factor (GDNF) and ciliary neurotrophic factor (CNTF) in the substantia nigra (SN). Interestingly, treatment with EP prevented degeneration of …
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Photorejuvenation Induced by 5-Aminolevulinic Acid Photodynamic Therapy in the Patients with Actinic Keratosis: A Histological Analysis
… I examined the specimens with routine and immunohistochemical staining and evaluated the parameters associated with photoaging using image analysis. Results: After ALA-PDT, the mean epidermis thickness and inflammatory infiltrate in the dermis were reduced. The total collagen volume in the …
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Expression of Bax Predicts Outcome in Advanced Gastric Cancer Patients Treated With 5-fluorouracil and Platinum Palliative Chemotherapy
… treated with 5-FU and platinum chemotherapy. Immunohistochemical staining for Bax with pretreatment biopsy specimen may be useful in selecting FOLFOX regimen as a treatment option for these patients.
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