Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"immune control"”.
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Immune Control of Hepatitis B Virus infection by innate lymphocytes
… of the role of innate lymphocytes in the control of HBV infection might eventually facilitate the development of new cell-based immunotherapies. We have quantified the frequencies and cytokine profiles of natural killer (NK), natural T (NT), natural killer T (NKT) and T cells in a group …
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Of Mice and Men: Studying Innate and Adaptive Immunity Against the Epstein-Barr Virus
… in vivo, but most immunocompetent individuals control EBV infection successfully without the occurrence of disease. Cells of the innate immune system act in synergy to provide a first line of defense against pathogens. Here we describe that dendritic cells (DCs), matured with viral products or …
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Alergia alimentar - temporalidade X antigenicidade
… (2) and Saline (3). In the second experiment, control group - C1 was submitted to oral tolerance induction protocol (7 day oral exposure followed by 2 immunizations with 100ug of OVA) and C2 to immunization protocol with 100ug of OVA. The experimental group was immunized twice with 100ug of …
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Bringing Til Therapy Beyond Melanoma: Advancing The Treatment of Advanced Pancreatic and Ovarian Cancers
… so far, there is still evidence for the role of immune control in these cancers as evidenced by presence of tumor-infiltrating lymphocytes (TIL) correlating with increased survival. Since <em>in vivo</em> manipulation of TIL through CBI does not seem to be sufficient to generate a strong clinical …
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Effects of galectins and antibodies in HIV infection; Novel Assays
… glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. An important tool in detecting and studying bnAbs, are …
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Tumor Immunotherapy: Mechanisms of Acquired Resistance and Characterization of Immune Related to xicities
… remission. Second, there are often dose-limiting immune related adverse effects associated with immunomodulation.</p> <p>In order to understand the mechanisms employed by tumors to evade immunotherapeutic responses, we established a murine model of melanoma designed to elucidate the molecular …
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Characterising the immunopeptidome in hepatitis B
… not been successful in achieving the long-term immune control required for functional cure. The display of HBV-derived peptides on major histocompatibility class I (MHC-class I, human leukocyte antigen (HLA) class I in humans) molecules on the cell surface is crucial to mount antiviral immune …
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Identification and Knockout of Immunodominant Endogenous Retroviral Antigen in Murine Tumor Models
… env. The envKO tumors were more susceptible to immune control at varying degrees compared to control knockout cells in vivo. CT26 envKO tumors were spontaneously rejected and MC38 envKO tumors grew much slower compared to the control tumors. Both B16F10 and 4T1 envKO tumors were characterized by …