Global ETD Search
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Showing 1 to 2 of 2 for “"imidazole compounds"”.
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Investigation of bioactive scaffolds as antimicrobials
… When co-administered with an antibiotic, such compounds can restore the biological activity of an antibiotic towards a resistant bacterial strain. In the Copp group, ongoing studies have found that compounds containing a polyamine moiety can display intrinsic antibacterial activity and …
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The Chemical Synthesis of Model Catalysts Related to Enzymes
… thesis involve the chemical synthesis of model compounds designed to explore how trypsin and chymotrypsin may function. Since several lines of evidence indicate a catalytic role for histidine residues in these enzymes, it was proposed to prepare imidazole derivatives with carefully designed side …