Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"imaging flow cytometry"”.
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Light field microscopy for 3D imaging flow cytometry
… level requires technologies enabling high speed imaging and sample throughput. This has motivated the evolution of flow cytometry, which uses microfluidics to measure the fluorescence and scattering signals of thousands of cells per second, towards imaging flow cytometry, which allows spatial …
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Silicon based photonic crystal coupled to an optical cavity for highly sensitive biodetection
… in disease diagnosis, DNA sequencing, cellular imaging, flow cytometry, forensics, and monitoring processes in biological systems. In order to achieve better sensitivity and higher signal-to-noise ratio (SNR), metal-enhancement fluorescence and nano-engineered surfaces were used to augment the …
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3D material cytometry (3DMaC): High-throughput, high replicate screening of materials using flow cytometry
… such methods are lacking. This thesis shows how flow cytometry can be adapted to the study of biomaterials. Flow cytometry allows for the automated collection of a large number of unique events in a short time period and is already widely used for cell analyses. Here, biomaterial, specifically …
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Making computer vision Methods accessible for cell classification
… is described along with its use for classifying imaging flow cytometry data. Further software related advances include the first demonstration of a deep learning based model designed to classify biological images with a user-friendly interface. Finally, blood smear images of malaria-infected …
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PROFILING EFFUSION CELLS BY QUANTITATIVE ANALYSIS OF MORPHOLOGY AND DIFFRACTION IMAGING PATTERNS
… a label-free method of polarization diffraction imaging flow cytometry (p-DIFC) for quantitative profiling of cell morphology in PPE samples and their correlations to the texture features of cross-polarized diffraction image (p-DI) pairs. To establish the morphology implications of the measured …
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The dynamics of anti-tumour responses generated by chimeric antigen receptor-modified immune effector cells
… products. Population-based assays such as flow cytometry give a snapshot of these complex cellular systems, but do not allow one to study the fate of individual cells over time. Therefore, the aim of this thesis was to apply flow cytometry, time-lapse imaging and singlecell tracking to …
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Elucidating the effects of dietary change on replicative ageing in Saccharomyces cerevisiae
… in the process of replicative ageing. We used imaging flow cytometry to monitor parameters and fluorescence levels of different markers of ageing and bulk RNA-sequencing to follow transcriptome changes in yeast cells during ageing. One particular focus of our research was the change in …
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Effector Cells and Mechanisms in Chronic Spontaneous Urticaria
… release (BHR) from CSU patients, basophil flow cytometry. Baseline UAS7 correlated with serum HRA (r=0.58, p=0.0045), and anti-IgE-induced BHR (r=0.40, p=0.0666).HRA+CSU patients (n=8) had a more severe disease than HRA- CSU patients (n=14) (p=0.0152). Based on the ROC analysis for UAS7 at …