Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"iduronic acid"”.
-
Biological Functions of Iduronic Acid in Chondroitin/Dermatan Sulfate in Tumor and Brain Development
… units (i.e. N-acetylgalactosamine and glucuronic acid/iduronic acid). CS/DS is a very dynamic structure, as it can be greatly modified by epimerization and sulfation. Epimerization is catalyzed by two enzymes, DS-epimerase 1 (DS-epi1) and 2 (DS-epi2), resulting in the formation of iduronic acid …
-
FROM GENE TO STRUCTURE: Formation of Iduronic Acid in Dermatan Sulfate by Two DS-epimerases
… of N-acetylgalactosamine and glucuronic acid/iduronic acid. Formation of iduronic acid through epimerisation of glucuronic acid is a key modification in dermatan sulfate biosynthesis. In the present thesis two enzymes have been identified that catalyzes this reaction, i.e. DS-epimerase 1 …
-
Analysis of the Structural Units of Sulfated Glycosaminoglycans by High Performance Ion Exchange Chromatography
… structural units of heparin produced by nitrous acid deamination were stoichiometrically reduced with NaB('3)H(,4) and analyzed by high performance ion exchange chromatography to obtain resolution of the four primary disaccharide units of heparin; 4-O-((beta)-D-glucopyranosyluronic …
-
Synthetic studies of heparan derivatives: Glycosyl couplings and post-glycosylative modifications
… units of D-glucosamine and either D-glucuronic acid (D-GluA) or L-iduronic acid (L-IdoA), and support variable degrees of sulfation which can interact with a large number of proteins with diverse biological functions. HS oligosaccharides can be constructed from readily accessible D-GlcN and …
-
The Characterization of Glycosaminoglycans and Metallic Dianions in the Gas Phase
… to the prototypical monosaccharide residue Iduronic Acid has been investigated using a combined molecular mechanics and quantum chemical approach. Merck Molecular Force Field 94’ has been utilized to generate candidate structures for higher level B3LYP, PW91PW91, M05-2X and MP2 calculations …