Global ETD Search
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Showing 1 to 7 of 7 for “"idiopathic intracranial hypertension"”.
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Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is common in obese women and can lead to significant visual impairment. The cause of IIH is unknown and management controversial, due to the lack of prospective trials. This thesis provides a comprehensive review of the aetiology and management of IIH. The …
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Investigation Into The Molecular Mechanisms Underlying Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is a neurological disorder characterised by raised cerebrospinal fluid (CSF) pressure in the absence of any intracranial pathology. IIH mainly affects obese women between the ages of 15 and 45. Two possible mechanisms that could explain the increased CSF …
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Obesity, 11β-hydroxysteroid dehydrogenase and metabolic changes in the pathogenesis of idiopathic intracranial hypertension
Idiopathic intracranial hypertension (IIH) is a blinding condition amongst the young obese female population characterised by elevated intracranial pressure (ICP). The aetiology of IIH is not known and, as highlighted in the 2005 Cochrane review, an evidence base for treatment has not been …
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Novel model of cerebrospinal fluid dynamics based on hemodynamically driven cyclic brain compliance variation
… representing: the ventricular system, the intracranial subarachnoideal space, and the spinal subarachnoideal space. The implemented driving function represents the blood volume variation with time produced by the cardiac cycle. In turn it detennines cyclic changes in brain parenchyma …
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Computational modelling of global haemodynamics and its interaction with cerebrospinal fluid and brain dynamics with application to essential hypertension
… neurological pathologies, secondly arterial hypertension. The work presented in this thesis consists of a multiscale model of the global, arterio-venous circulation in the entire human body. The present model represents an enhanced version of the original Müller-Toro mathematical model. It …
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The Measurement and Interpretation of Intracranial Pressure
The intracranial pressure (ICP) is the most commonly monitored brain parameter in neurocritical care. Its rise, which may be benign, acute or chronic, is a common yet serious problem. ICP can rise because of a number of critical medical conditions such as hydrocephalus, traumatic brain injury, …
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Dynamics of cerebral fluids in patients suffering from hydrocephalus and pseudotumour cerebri
… compensation. Since the introduction of intracranial pressure (ICP) monitoring, the studies of CSF dynamics have revealed unique information about the intracranial circulation and opened new opportunities for diagnosis and treatment of hydrocephalus and pseudotumour cerebri. The …