Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"iPSC-derived neuronal model"”.
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Understanding the molecular bases of neurodegeneration: From the structural characterisation of the aggregates to the establishment of an iPSC-derived neuronal model
… this, the development of accurate disease models is necessary for the elucidation of the biological mechanisms central to the pathology, and for the discovery of effective therapies targeting such mechanisms. Therefore, in the second part of this thesis, we establish and characterise three …
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The role of Synaptic Genes NRXN1 and SHANK3 in Autism: an induced pluripotent stem cell study
… with the structural or functional aspects of neuronal connections or synapses. However, it is poorly understood how the loss of function of these synaptic genes contribute to the neuronal morphology, network physiology and atypical communication between brain cells. This thesis aims to first …