Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"hypoxia-inducible factor 2 alpha"”.
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Harnessing the Immunomodulatory Potential of Radiofrequency Ablation to Improve Therapeutic Outcomes in Pancreatic Ductal Adenocarcinoma
… expression of macrophage migration inhibitory factor (MIF) levels, and elevated hypoxia-inducible factor 2-alpha (HIF2α) expression were among the important componentsof the TME that were examined. Our data shows notable tumor-associated changes post-RFA, highlighting how EUS-RFA may enhance …
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Studies on renal progenitor cells and kidney cancer
… show that the SLC6A3 expression is affected by hypoxia inducible factor 2 alpha (HIF-2α), an important protein in the cellular oxygen sensing system, which is ubiquitously expressed in the constantly pseudohypoxic ccRCC tumors. We further demonstrate that hypoxia induces SLC6A3 expression in …
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Mechanisms underlying establishment and maintenance of pregnancy
… the mechanisms underlying maternal adaptation to hypoxia during early pregnancy remain unclear. In this study, using a knockout mouse model, we show that the transcription factor hypoxia-inducible factor 2 alpha (Hif2α), which is induced in subluminal stromal cells at the time of implantation, …
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Molecular mechanisms regulating implantation
… steroid hormone receptor, estrogen receptor alpha (ESR), in order to exert its effects during pregnancy. The studies reported here investigate E’s action via ESR1 and its downstream targets in uterine physiology and is written in three parts. The first part is an investigation of role of …
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The role of ERα in the uterus during embryo implantation and in the ovary during ovarian tumorigenesis
… steroid hormone receptor, estrogen receptor alpha (ERalpha) or beta (ERalpha, to fulfill these biological processes. This dissertation investigates estrogen’s action via ERalpha in uterine physiology and ovarian pathophysiology and is written in two parts. The first part is an investigation …