Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 104 for “"hypothalamic-pituitary-adrenal"”.
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The Action of Endotoxins Upon The Hypothalamic - Pituitary - Adrenal System
Made available in DSpace on 2014-12-09T23:34:03Z (GMT). No. of bitstreams: 1 6915353.pdf: 3667204 bytes, checksum: d370676f499205f15c4654561bd8a469 (MD5) Previous issue date: 1969
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Transcriptome analysis of the hypothalamic-pituitary-adrenal axis in the experimentally domesticated fox
… in activity of the hormonal stress response, or hypothalamic-pituitary-adrenal (HPA) axis, has been associated with different personality traits and coping styles in humans and animals, while its dysregulation has been implicated in psychological disorders. The molecular basis of HPA axis …
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The FitzHugh-Nagumo model dynamics with an application to the hypothalamic pituitary adrenal axis
… cortisol secretion, which is controlled by the hypothalamic pituitary adrenal axis (HPA). Existing mathematical models for cortisol secretion do not include the entire cortisol secretion process, from the neural firing of cortopin releasing hormone(CRH) in the hypothalamus to cortisol secretion …
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EARLY LIFE STRESS EXPOSURE AND HYPOTHALAMIC PITUITARY ADRENAL AXIS: FROM MECHANISMS TO PERIPHERAL BIOMARKERS OF VULNERABILITY
È noto come fattori ambientali, quali ad esempio l’esposizione ad eventi stressanti nel corso della vita, siano in grado di aumentare il rischio di sviluppare disturbi psichiatrici stress correlati che si caratterizzano per differenti entità ed età di insorgenza a seconda del momento e della …
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Role of testosterone in mediating prenatel ethanol effects on hypothalamic-pituitary-adrenal activity in male rats
… has marked effects on development of the hypothalamic-pituitary-adrenal (HPA) and -gonadal (HPG) axes. E rats show HPA hyperresponsiveness to stressors and altered reproductive function in adulthood. Importantly, prenatal ethanol differentially alters stress responsiveness in adult males …
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The activity and functioning of the hypothalamic-pituitary-adrenal axis of the red deer stag (cervus elaphus)
… in the activity and responsiveness of the adrenal gland in red deer stags were quantified by measuring 24 h endogenous cortisol secretory profiles and plasma cortisol responses to either administration of exogenous ACTH or a standardised stressor during November (period of velvet growth), …
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Circadian activation of the hypothalamic-pituitary-adrenal axis may affect central, but not peripheral, effect of lithium in conditioned taste aversion learning in rats
Activation of the hypothalamic–pituitary–adrenal (HPA) axis has been implicated in conditioned taste aversion (CTA) learning induced by lithium chloride. This study investigated if circadian activation of the HPA axis affects the lithium-induced CTA formation. The pairing of conditioned stimulus …
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Estrogen Regulation of the Pregnant Baboon Placental 11β-Hydroxysteroid Dehydrogenase (11β-HSD)-Catalyzed Metabolism of Cortisol and Cortisone and Its Effect on the Development of the Fetal Hypothalamic-Pituitary-Adrenal Axis
… the fetus culminating in activation of the hypothalamic-pituitary adrenal axis of the baboon and the ontogenesis of rate-limiting steroidogenic enzymes culminating in <em>de novo</em> F secretion. Protein kinase A (PK-A) activity in the baboon fetal adrenal gland cytosolic fraction was …
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Alterations of the Corticotropin Releasing Hormone Receptor System Following Early Life Stress and Ethanol Self-Administration in Rhesus Monkeys
… to identify how ELS and EtOH drinking affected hypothalamic-pituitary-adrenal (HPA) axis function and CRH receptor binding. We used an accepted ELS model of maternal separation with nursery-reared (NR) and mother-reared rhesus monkeys induced to self-administer EtOH or control solution for over …
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The effects of early developmental stress and exercise intervention on neurodegeneration in a rat model of Parkinson's disease
… and this has been related to chronic enhanced hypothalamic-pituitary-adrenal axis activity. Animal studies have shown that maternally separated rats exhibit increased anxiety- and depression-like behaviour in adulthood, although other evidence shows hyperactivity and impulsivity in such cases. …
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Effects of periconceptional undernutrition and twinning on ovine pregnancy
… glucose disposal following a glucose challenge. Hypothalamic-pituitary-adrenal axis tests in these fetuses showed decreased pituitary adrenocorticotropin hormone response to direct stimulation but increased adrenal response to decreased cortisol negative feedback. Twin fetuses grew more slowly in …
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Understanding The Role Of Nutritional Stress In The Adult And Developing Zebra Finch
… the effects NS on females are still unclear. The hypothalamic-pituitary-adrenal axis (HPA) has been implicated in this process. However, evidence directly linking HPA functioning to the deficits due to NS have inconsistently shown elevations in CORT. Additionally, the effects of early NS on the …
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Stress And Social Relationships: The Role Of Corticosterone In The Formation And Maintenance Of Pair Bonds In The Monogamous Zebra Finch (taeniopygia Guttata)
… rodents, suggest that activation of the hypothalamic-pituitary-adrenal axis (HPA) in males increases attraction for females. Across species, females are understudied, but evidence from the prairie vole suggests HPA activation impairs formation of partner preference, the first step in …
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Analyzing the Interaction Between Melanocortin 5 Receptor, Melanocortin Receptor Accessory Protein 1, and Melanocortin 2 Receptor in Rainbow Trout
… relationships may play a significant role in Hypothalamic-Pituitary-Adrenal/Interrenal axis activation. This research demonstrated that rtMC5R can be successfully expressed and functionally activated in CHO cells and, in a manner similar to mammals, α-MSH is the preferred ligand for rtMC5R. …
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Translational Regulation in Excitatory Neurons Controls Stress Reactivity and the Antidepressant Response to Ketamine
… whereas acute stress is adaptive and mediated by hypothalamic-pituitary-adrenal axis activation. Ketamine produces rapid antidepressant effects, partly through mammalian target of rapamycin complex 1 (mTORC1) signalling, which phosphorylates 4E-Binding Protein 1 and 2 (4E-BPs) to promote synaptic …
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Trauma and psychophysiologic reactivity: menstrual phase, posttraumatic stress disorder, and performance on a loud tones task
… variety of effects these hormones have on the Hypothalamic-Pituitary Adrenal (HPA) axis, glucocorticoids, stress and anxiety homeostasis, and conditionability. We hypothesized greater reactivity for participants with PTSD, and that menstrual cycle would moderate the effects of PTSD and …
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Reciprocal Relationships Between the Neuroendocrine System and Lymphoid Cells
… understood. Acute stressors activate both the hypothalamic-pituitary-adrenal axis and sympathomedullary system, which results in increased plasma concentrations of glucocorticoids and cathecholamines. Lymphoid cells possess receptors for both of these stress-related hormones, and activation of …
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The Effect of Increased Sleep on the Circadian Rhythm of Salivary Cortisol Concentrations
<p>Cortisol is a salivary marker for the hypothalamic-pituitary-adrenal axis (HPA) component of the stress response. The activity of the HPA demonstrates a circadian rhythm. It is well known that sleep deprivation increases cortisol concentrations. In this study, we looked at the effect of an …
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Unravelling the role of tryptophan metabolism in the microbiota-gut-brain axis: focus on the effects of stress and exercise
… are impaired in stress-related disorders: the hypothalamic-pituitary-adrenal axis and tryptophan metabolism. This crosstalk has been widely characterised following chronic stress, in stress-related disorders and gastrointestinal disorders comorbid with psychological distress. The acute …
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