Global ETD Search
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Showing 1 to 6 of 6 for “"hyperuricaemia"”.
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Biochemical Studies Of Human Hyperuricaemia
… of the enzyme which are linked neither to hyperuricaemia nor to gout. Statistical analyses have shown a significant increase in the enzymic activity of erythrocyte phosphoribosylpyrophosphate synthetase in both the hyperuricaemic groups compared with the controls. No correlation of age with …
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Genetics of serum urate regulation in human health and disease
… pressure. Excessively high serum urate levels (hyperuricaemia) are associated with a wide range of diseases. With the exception of gout, where monosodium urate crystals are known to trigger a painful inflammatory response, both the causality and the underlying mechanisms linking hyperuricaemia …
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Uric acid metabolism in the Dalmatian coach hound
… abnormalities of uric acid metabolism, namely hyperuricaemia, hyperuricosuria and increased renal uric acid clearance. These properties are associated with hypoallantoinaemia and hypoallantoinuria. A result of these abnormalities is a high incidence of urate urolithiasis in this breed. Other …
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Renal and Blood Pressure Effects of Xanthine Oxidase Inhibitors in the FAST trial
… renal function and blood pressure and control of hyperuricaemia with xanthine oxidase inhibitors. Data from the Febuxostat versus Allopurinol Streamlined (FAST) trial is presented in three studies:1) Up-Titration of Allopurinol in Patients with Gout. Patients recruited into the FAST trial have …
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Kinetic and metabolic studies in HPRT deficiency
… of T.K., I could monitor the progress of his hyperuricaemia and observe the effects of therapy throughout the duration of this project.