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Showing 1 to 20 of 32 for “"hyperphagia"”.
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The Role of Affect in Hypothalamic Hyperphagia
Made available in DSpace on 2014-12-10T21:07:18Z (GMT). No. of bitstreams: 1 7212087.pdf: 3671044 bytes, checksum: 232e3f46a36d1d18b3388dfaa433e14c (MD5) Previous issue date: 1971
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An Assessment of Obesity and Hyperphagia In Individuals With Smith-Magenis Syndrome
… the growth and potential influence of hyperphagia in a cohort of individuals with SMS. A retrospective chart review was conducted of 78 individuals with SMS through Baylor College of Medicine (BCM) at Texas Children¡¯s Hospital (TCH.) All documented height and weight measurements were …
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Neuroanatomical specificity of prolactin-induced hyperphagia and expression of fos-like immunoreactivity following central administration of prolactin
… of PRL twice daily at a dose known to promote hyperphagia (2 [Special characters omitted.] /0.5 [Special characters omitted.] ). The rats were sacrificed one hour after their last injection and their brains processed for Fos-fir. Significant changes in expression of Fos-lir were observed only …
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The Effects of Allopregnanolone on Feeding: A Behavioural Investigation
… a neurosteroid, has been shown to produce hyperphagia in rodents. The effects of allopregnanolone on appetitive and Consummatory behaviors associated with feeding were examined. Allopregnanolone had no effect on consummatory behaviors, as measured by the taste reactivity test. In the …
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MOLECULAR MECHANISMS OF APPETITE AND ENERGY BALANCE
… obesity, driven by sustained day-and-night hyperphagia. Deletion of ELKS in the dorsomedial hypothalamus, but not in other key feeding nuclei, also caused obesity and hyperphagia. Nkx2.1 neurons in the DMH are glutamatergic, co-express orexin-A, and project to brain reward centers. Synaptic …
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The role of Arginyltransferase 1 in body weight homeostasis
… less than WT mice despite consuming more food (hyperphagia). We also found that, similar to WT mice on normal chow, ATE1-KO mice remain responsive to leptin on NC. However, ATE1-KO mice had significantly lower circulating plasma leptin than wild type mice on both diets. This explains (at least …
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Effect of Depression Treatment on Somatic Depressive Symptoms and Cardiometabolic Biomarkers among People without Diabetes
… the Hopkins Symptom Checklist-20 (SCL-20) items: hyperphagia (“overeating” item), poor appetite (“poor appetite”), hypersomnia (“sleeping too much”), disturbed sleep (“sleep that is restless or disturbed”) and SCL-15 (mean of items not pertaining to appetite or sleep). I calculated insulin …
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Transport and Metabolism in the Gastrointestinal Tract of Diabetic Animals:a study involving lean and (ob/ob) mice
… mucosa. The response was clearly an effect of hyperphagia, but, unlike other hyperphagic states, the size of the intestine did not regress when food consumption returned to normal. There was little effect of the (ob/ob) syndrome on the transepithelial transport of glucose or the unidirectional …
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Regulation of Energy Balance by Dietary Protein
… that protein restriction triggers a compensatory hyperphagia to facilitate the acquirement of the animal's protein needs whereas protein excess elicit hypophagia as the animal's protein requirement is met at a lesser calorie intake. However, the effects of dietary protein on energy expenditure and …
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Hypothalamic control of energy rheostasis during metabolic challenges, pregnancy, and lactation
… unique metabolic states defined by increased hyperphagia. Chemogenetic manipulation, fiberphotometry, and spatial transcriptomics revealed that pregnancy increases AgRP neuron activity and decreases POMC neuron activity in the arcuate nucleus. Chemogenetic activation of POMC neurons or …
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Role of 5-ht2c receptor density on behaviour in mice
… receptor expression would improve mood, cause hyperphagia, obesity and hyperlocomotion. In order to investigate these hypotheses mouse models that either over- or under-expressed the 5-HT2C receptor were implemented. The 5-HT2C receptor expression pattern and levels were confirmed in all mouse …
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Mapping Major Genetic Factors of Obesity
… pathways that affect metabolism. Behaviors like hyperphagia and exercise are important aspects of both the development and treatment of the disease. All of these factors contribute to the increase prevalence of obesity, which current treatments have not been able to adequately address. The …
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The Relationship Between Caring For Individuals Diagnosed With Prader-Willi Syndrome And Caregiver Stress
… diagnosed with Prader-Will syndrome (PWS): hyperphagia and explosive behaviors. Other variables being explored relate to variables not directly to the individual being cared for: coping strategies of the caregiver, perceived social supports, and resources/respites. Methods: For this …
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Effects of Ventromedial Hypothalamic Lesions on Food-Reinforced Fixed Ratio Responding
… area of the hypothalamus become obese due to hyperphagia. This striking effect on ad libitum food intake is sometimes accompanied by an increase and sometimes by a decrease in other measures of propensity to eat such as food-rewarded lever pressing. The current experiments attempt to discover …
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The Nature of Night Eating Syndrome: Using Network Analysis to Understand Causal Symptomological Relationships
… that nocturnal ingestion of food and evening hyperphagia would present as the most central symptoms within the psychopathology network of NES compared to other symptoms. A Gaussian graphical model (GGM), utilizing a graphical least absolute shrinkage and selection operator (GLASSO) method, was …
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Functional responses of cardiac and skeletal muscle mitochondria to short-term obesity: are all obesities the same?
… lateralis) and Ob/Ob mice following 4-6 weeks of hyperphagia versus their respective lean controls. Glucose tolerance tests were administered in lean, summer active squirrels (summer); hyperphagic obese, pre-hibernation period squirrels (prehib); and 5-week-old leptin-deficient (ob) and control …
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Interactive Effects of Macronutrients on Obesity and Metabolic Syndrome Development
… role of marginal protein deficiency in driving hyperphagia and increased adiposity, but have refuted other studies showing increased adiposity by dietary fat and fructose. When protein is marginally deficient, replacing glucose with fat or fructose unexpectedly spared amino acids and enhanced …
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Life Without GPR7, the Neuropeptide W1 Receptor: Regulation of Energy Homeostasis by GPR7 and its Endogenous Neuropeptide Ligands
… nucleus of the hypothalamus (VMH) resulting in hyperphagia and obesity. To identify genes involved in the hypothalamic regulation of energy homeostasis, we employed a screen to search for genes that were dysregulated in GTG induced obese mice. In this screen, GPR7, the endogenous G …
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Developmental signaling pathways in adult energy homeostasis
… involvement of Hh signaling in mediating the hyperphagia driven obesity observed in certain ciliopathies is explored in Chapter 3. Emerging evidence suggests cilia play an important role in the regulation of feeding behavior. In mammals, the hedgehog pathway is dependent on the primary cilium …
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Chickens Selected for High Body Weight Show Relative Impairment in Fatty Acid Oxidation Efficiency and Metabolic Flexibility in Skeletal Muscle and White Adipose Tissue
… (LWS) juvenile body weight. We hypothesized that hyperphagia and obesity in juvenile HWS chickens are associated with altered fatty acid oxidation efficiency and metabolic flexibility in tissues associated with energy sensing and storage, and relative cellular hypertrophy in white adipose tissue. …
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