Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"hyperdiploidy"”.
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Trisomies in Hematologic Malignancies
… and myelodysplastic syndromes (MDS), and on high hyperdiploidy ? gains of multiple chromosomes ? in childhood acute lymphoblastic leukemia (ALL). In the first two articles, AML and MDS cases with +8 as the seemingly sole abnormality were studied with fluorescence in situ hybridization (FISH) …
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Discovery of new biomarkers of mild cognitive impairment and Alzheimer's disease risk in buccal cells using laser scanning cytometry
… a significant increase in DNA content and hyperdiploidy (as measured by DAPI fluorescence) as well as a significant decrease in neutral lipid content (measured by Oil Red O staining) in buccal cells of MCI (n=22) and AD (n=15) compared to controls (n=37) from the SAND study. Using another …
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Genetic changes in the development of multiple myeloma
… initiating events (i.e. IgH translocations or hyperdiploidy) of this multistep process while others occur at later stages. In this study, interphase-FISH showed that initiating events are present in MGUS (n=187) and asymptomatic MM (SMM, n=128) at similar frequencies as found in MM (n=400) (the …
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Cytogenetic abnormalities in Acute Myeloid Leukemia in Sweden. A population based study.
The impact of cytogenetic findings in AML was analyzed in the large population-based Swedish AML registry. Karyotypic patterns differed by age: t(8;21), inv(16) and t(11q23) were more common in younger patients, whereas loss of 5q, 7q and 17p, monosomal karyotype (MK) and complex karyotype (CK) …