Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"hygiene hypothesis"”.
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Sex and Fear: Mathematical models of mate choice, parental care, and maladaptive anxiety
… is in some ways analogous to the well-known ``hygiene hypothesis" of inflammatory and autoimmune diseases.
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Host parasite interaction in a mouse model of inflammatory bowel disease
… with intestinal parasites is common.The hygiene hypothesis suggests lack of infection predisposes to the development of IBD ingenetically susceptible people. However, little is known immunologically about how gutparasites alter IBD progression. We have used mdrla KO mice on an FVB …
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Detection of staphylococcal enterotoxins in patients with rheumatoid arthritis or closed fracture
… Potential pathogenic mechanisms include the hygiene hypothesis and molecular mimicry. Due to the widespread prevalence of RA, it has been hypothesised that the pathogenesis could involve a common bacterium. In RA, one potential bacterial candidate that has been suggested is S.aureus. Current …
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The relationship between immunization and food allergy and sensitisation in South African children
… in children are not clear. In light of the hygiene hypothesis, vaccinations may contribute towards to a predominant allergen specific response or exposure to the virus or microbe in the vaccine may decrease the risk for allergy. Previous studies have shown that the effect of vaccinations on …
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POPULATION GENETIC APPROACHES FOR THE STUDY OF COMPLEX TRAITS: FOCUS ON INFECTIOUS AND AUTOIMMUNE DISEASES
… and allergic conditions being the outcome (hygiene hypothesis). Quite obviously, the presence of a functional variant is a prerequisite for selection to act, and the identification of non-neutrally evolving genes has been regarded as a strategy complementary to classical clinical and …
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Gut bacteria, regulatory T cells and allergic sensitization in early childhood
The hygiene hypothesis postulates that reduced or altered microbial exposure early in life may lead to impaired immune maturation and, as consequence of this, development of allergic disorders. Thus, we examined if the infantile gut microbiota was related to the postnatal T cell development in vivo …
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Characterisation of the anti-inflammatory potential of ES-62 in autoimmune disease
… diseases, coincident with recent improvements in hygiene; a trend not observed in parasite-endemic countries. Therefore, the ”hygiene hypothesis” proposes that these trends are directly associated, by predicting that in the absence of helminth infection, there is a lack of parasite-induced …
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The effect of parasite antigen on experimentally induced ‘asthma’ in lambs
There is a worldwide consensus that the incidence of asthma and allergy is exhibiting a rising trend in western societies. There is also epidemiological evidence that New Zealand children raised on farms are less likely to experience asthma than those in urban environments. The aims of this study …