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Showing 1 to 1 of 1 for “"hydroxybupropion"”.

  1. Pharmacokinetics of Bupropion and its Pharmacologically Active Metabolites in Pregnancy

    Fokina, Valentina MikhaylovnaThe University of Texas Medical Branch at Galveston2021

    … of pharmacologically active metabolites, namely hydroxybupropion (OHBUP), threo- (TB) and erythrohydrobupropion (EB). CYP2B6 is the primary enzyme catalyzing the formation of OHBUP; the latter is the main plasma metabolite of bupropion and is thought to contribute majorly to pharmacological …

    utmb Repository record