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Showing 1 to 3 of 3 for “"hydroxy radical"”.
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Melatonin's Protection against DNA Damage by the Iron (III)-Adriamycin Complex.
… ROS formed with downstream production of the hydroxy radical via the Fenton reaction. 4) Fe<sup>+3</sup>-Adriamycin (1:2) intercalates into DNA to the same degree as uncomplexed adriamycin. 5) Melatonin also binds to DNA but not by intercalation. These experiments indicate that the …
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Syntheses of a Tin (IV) meso-Tetra(4-pyridyl) Porphyrin Dichloride-Tetrachlorobis (Bipy)2 Ruthenium (II) Complex and Studies of Photophysical Properties of 1-Nitropyrene
<p>Development of a photosensitizer that can work in both aerobic and anaerobic environments would increase the robustness of the cancer treatment known as photodynamic therapy. The development of a photosensitizer was first attempted by synthesizing a tin (IV) meso-tetra (4-pyridyl) porphyrin …
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Molecular basis of MPTP-induced Parkinson's disease
… MPTP, was found to generate superoxide radical (⋅O₂⁻) during its autoxidation process. The generation of ⋅O₂⁻ was detected by their ability to reduce ferricytochrome c. Superoxide dismutase (SOD) inhibited this reduction in a dosedependent manner. The rate of reduction of ferricytochrome …