Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"hydroaminoalkylation"”.
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A novel photocatalytic strategy for complex aliphatic amine synthesis and the total synthesis of alkaloids (−) FR901483 and (+)-TAN1251C
… reaction conditions, the photocatalytic olefin-hydroaminoalkylation procedure was shown to be compatible with a broad range of benzyl amine, aldehyde, and olefin substrates. A detailed study of the mechanism of the transformation is described, revealing an unusual 1,5-hydrogen atom transfer step …
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Selective Chemical Reactions for Nucleic Acid Sequencing and DNA-Encoded Library Synthesis
… efficient approach for the photoredox-catalysed hydroaminoalkylation between on-DNA secondary N-substituted (hetero)arylamines and vinylarenes is explored as a method to generate DELs with known bioactive architectures. The developed reaction proceeds efficiently with a broad and well-explored …
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New strategies for the synthesis and functionalization of aliphatic amines
The invention of catalytic processes that convert feedstock chemicals into pharmacologically-privileged amines is a landmark challenge in organic synthesis. This thesis describes the development of three novel transition-metal catalyzed processes for the synthesis of alkylamines that attempts to …