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Showing 1 to 2 of 2 for “"hybrid stochastic simulation algorithm"”.
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Analysis and Application of Haseltine and Rawlings's Hybrid Stochastic Simulation Algorithm
Stochastic effects in cellular systems are usually modeled and simulated with Gillespie's stochastic simulation algorithm (SSA), which follows the same theoretical derivation as the chemical master equation (CME), but the low efficiency of SSA limits its application to large chemical networks. To …
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Stochastic Modeling and Simulation of Multiscale Biochemical Systems
Numerous challenges arise in modeling and simulation as biochemical networks are discovered with increasing complexities and unknown mechanisms. With the improvement in experimental techniques, biologists are able to quantify genes and proteins and their dynamics in a single cell, which calls for …