Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"hybrid dysgenesis"”.
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Understanding Host Tolerance to Transposable Elements
… I take advantage of a unique phenomenon called hybrid dysgenesis in Drosophila melanogaster where naïve females devoid of P-element DNA transposon typically produce sterile offspring when mated with P-element carrying males. However, tolerant individuals are capable of producing viable gametes …
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Responses to transposon activity and genome damage during germline development
… transposon-induced sterility in Drosophila, P-M hybrid dysgenesis, as a model. I show that excessive activity of the P-element transposon in embryonic primordial germ cells (PGCs) leads to the accumulation of DNA double strand breaks (DSBs) and sustained cell cycle arrest prior to fully penetrant …