Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 120 for “"huntington"”.
-
Faraldsfræði Huntington sjúkdóms á Íslandi. 2008-2022
Inngangur: Huntington sjúkdómur (HS) er sjaldgæfur, ættlægur taugahrörnunarsjúkdómur sem einkennist af ofhreyfingum, geðröskun og heilabilun. Sjúkdómurinn erfist ríkjandi og stafar af cýtósín-adenín-gúanín þríkirnaþenslu í huntingtin geninu. Algengi er hæst í einstaklingum af evrópskum uppruna en …
-
Genetic and anthropometric studies of aging in Huntington disease
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
-
American Machiavelli: Samuel P. Huntington the Author of Grand Strategy
<p>Samuel P. Huntington was one of the most influential political scientists of the 20th century, authoring a series of influential “concepts” and “paradigms” that have had tremendous impact on both scholarship and political practice. Historians have made great efforts to chart the anomalous, …
-
Marine Interstitial Tardigrades and Other Meiofauna of Huntington Beach, South Carolina.
<p>At Huntington Beach, SC meiofauna distribution was investigated. The purpose of the study was to determine tardigrade species present and any significant differences in the distribution pattern. Meiofauna were analyzed to determine if there were significant differences in their distribution …
-
Silencing mutant Huntingtin by RNA interference for the treatment of Huntington Disease
Huntington Disease (HD) is a dominantly inherited neurological disease attributed to a CAG expansion within the HD gene. The HD mutation gives rise to a polyglutamine expansion in exon 1 of the protein huntingtin (Htt). Since the discovery of the HD mutation in 1993, various HD gene mouse models …
-
Analysis of Huntington Disease Caregiver Quality of Life Using The Enroll-Hd Population
<p>Huntington disease (HD) is a neurodegenerative condition inherited in an autosomal dominant manner caused by a CAG triplet repeat expansion within the <em>HTT</em> gene. Thus, HD is unique among neurodegenerative disorders with a caregiver population often burdened by both the caregiver role and …
-
The role of a genetic counsellor in a support group for Huntington disease
… of a genetic counsellor in a support group for Huntington disease. This study examines the role of a genetic counsellor in a Huntington Disease support group, specifically the Huntington’s Association of South Africa (HASA). A qualitative research approach was used to interview 17 people who …
-
Said-Huntington Discourse Analyzer : a machine-learning tool for classifying and analyzing discourse
… I have developed a prototype tool "Said-Huntington Discourse Analyzer" that machine classifies news articles on a normative scale -- a scale that measures "clash of civilization" polarization in an article on the basis of conflict. The tool also extracts semantically meaningful …
-
Molecular investigation of the trinucleotide repeats within the Huntington disease gene in Southern Africa
Huntington disease (HD) is an autosom 1 dominant, progressive neurodegenerative condition, which usually presents in mid-life. The disease-causing mutation was identified in 1993 and entails the expansion of an unstable repeat (CAG)n within exon 1 of the, HD gene (IT-15). A polymorphic (CCG)n …
-
Veränderungen der cholinergen, dopaminergen und noradrenergen Transmitterfreisetzung und -wiederaufnahme in einem transgenen Mausmodell für Chorea Huntington
Chorea Huntington ist eine genetische Erkrankung des zentralen Nervensystems. Dabei führt eine Mutation vor allem im Striatum zu Neuronenverlusten, die von Symptomen wie Gewichtsverlust und Hyperkinesien begleitet werden. Das Krankheitsbild setzt im mittleren Lebensalter ein und führt unabänderlich …
-
Descripción de nuevos correlatos transcripcionales y de nuevas fuentes de biomarcadores en la enfermedad de Huntington
… potencial valor pronóstico en la enfermedad de Huntington (EH), una enfermedad neurodegenerativa mortal para la que no hay cura y que está causada por una expansión aberrante de una secuencia de repeticiones de trinucleótidos CAG en el exón 1 del gen de la Huntingtina (HTT). Aunque se ha …
-
A molecular investigation of Huntington disease; origins of the mutation and current prevalence in South Africa
Huntington disease (HD) is a devastating neurodegenerative condition characterised by a triad of symptoms: behavioural/psychiatric changes, cognitive decline and movement disorder. The dominantly inherited disease-causing mutation is an expanded trinucleotide (CAG) repeat in the Huntingtin(HTT) …
-
Identification of novel palmitoyl acyl transferases and characterization of the role of Huntingtin palmitoylation in Huntington Disease
… the polyglutamine tract in huntingtin as seen in Huntington Disease (HD) results in reduced association with HIP14 and decreased palmitoylation of huntingtin, which contributes to the formation of inclusion bodies and enhanced neuronal toxicity. By manipulating HIP14 levels through expression or …
-
"Exploring local civic citizenship surrounding the ""¡Huntington Park no se vende!"" campaign on Paseo Boricua in Chicago"
Citizenship is fundamentally defined by praxis--i.e., engagement in local and diverse forms of civic practices--rather than by a legal status tied to the nation-state (Tully, 2008). This dissertation research examined the participatory democracy practices of a community activist group that was …
Page 1 of 6