Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"human vascular endothelial cells"”.
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Biological activity of anthocyanins and their phenolic degradation products and metabolites in human vascular endothelial cells
Human, animal, and in vitro data indicate significant vasoprotective activity of anthocyanins. However, few studies have investigated the activity of anthocyanin degradation products and metabolites which are likely to mediate bioactivity in vivo. The present thesis therefore examined the vascular …
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The vascular and anti-inflammatory activity of Cyanidin-3-Glucoside and its metabolites in human vascular endothelial cells
… has been associated with a reduced risk of cardiovascular disease (CVD), which is supported by evidence from human, animal and in vitro studies. However, owing to anthocyanins’ poor bioavailability and extensive metabolism, it is likely their metabolites are responsible for their reported health …
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Role of 5-Lipoxygenase in Interleukin-4-Induced Oxidative Stress and Inflammation in Vascular Endothelium
Cardiovascular disease (CVD) including atherosclerosis is the leading cause of illness and death in the United States. The American Heart Association indicated that an estimated 81,100,000 American adults have one or more types of CVD and the estimated direct and indirect cost of CVD for 2010 is …
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Effect of Carbon Monoxide-Releasing Molecule-3 on the Severity of Endothelial Dysfunction Due to Elevation of Hydrostatic Pressure in an In Vitro Model of Compartment Syndrome
… osseofascial compartment. It leads to microvascular dysfunction, limiting oxygen and nutrient delivery, gas exchange, resulting in cellular anoxia, muscle necrosis and cell death. Currently, the only effective treatment is surgical fasciotomy. Recently, carbon monoxide (CO) delivered via …
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Therapeutic Application of Carbon Monoxide in Acute Limb Compartment Syndrome
… examine the effects of CORM-3-derived CO on microvascular dysfunction due to elevated compartment pressure within skeletal muscle, using clinically relevant models of CS. The efficacy of both CO and CORM-3 was tested in the rat, demonstrating that CORM-3, just like inhaled CO, was able to prevent …
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The relationship between glucose metabolism byproduct, D-lactate, and vascular endothelial cell dysfunction and possible role in diabetes
… mellitus is a chronic disease associated with vascular complications. Vascular endothelial dysfunction caused by increased endothelial cell apoptosis contributes to diabetic cardiovascular complications. The glucose metabolic by-product, D-lactate, is elevated in diabetics and it is unknown …
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Metabolic regulation of human vascular endothelial cell function in vitro
The vascular endothelium contributes to the maintenance of vascular health by regulating vascular tone and leukocyte adhesion, amongst others. The vasoregulatory actions of the endothelium are mediated through coordinated release of vasodilators such as nitric oxide (NO) and prostacyclin, and …