Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"human embryonic development"”.
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Probing early human embryonic development to characterize BMP signaling stimulators
… zur Identifizierung solcher Stimulatoren um ein humanes, hochdurchsatzkompatibles System zu erweitern – essentiell für die Übertragbarkeit identifizierter Verbindungen hinsichtlich der Wirksamkeit und Sicherheit auf humane Anwendungen in der Regenerativen Medizin. Dafür wurden Methoden entwickelt …
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CHARACTERISING THE REPROGRAMMING DYNAMICS BETWEEN HUMAN PLURIPOTENT STATES
Human pluripotent stem cells (hPSCs) exist in multiple states of pluripotency, broadly categorised as naïve and primed states. These provide an important model to investigate the earliest stages of human embryonic development. Naïve cells can be obtained through primed-to-naïve reprogramming; …
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A multi-lineage in vitro mouse embryo model derived exclusively from mouse embryonic stem cells
The mouse embryo has been a vital model to study human embryonic development and congenital diseases. As the mouse embryo implants, it undergoes drastic morphological changes to form the egg cylinder consisting of the epiblast (EPI), extraembryonic ectoderm (ExE) and visceral endoderm (VE), which …
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Identification and Analysis of Illegal States in the Apoptotic Discrete Transition System Model using ATPG and SAT-based Techniques
… Death, or Apoptosis, plays a critical role in human embryonic development and in adult tissue homeostasis. Recent research efforts in Bioinformatics and Computational Biology focus on gaining deep insight into the Apoptosis process. This allows researchers to clearly study the relation between …
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STUDIES OF B CELL DEVELOPMENT AND V(D)J RECOMBINATION
… of a mouse platform capable of producing fully humanized HCAbs. The Crescendo platform presents a unique opportunity to expand our understanding of how mouse B cell development functions by exploiting the features of heavy chain only antibody production. Furthermore, the platform enables the …