Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"human brain microvascular endothelial cells"”.
-
Untersuchungen zu intrazellulären Folgereaktionen von Neisseria meningitidis und Escherichia coli K1 in HBMEC (human brain microvascular endothelial cells)
… (ERK) im Verlauf von Infektionsassays in HBMEC (human brain microvascular endothelial cell) mittels Western Blot untersucht. Eine Zu- oder Abnahme in der Phosphorylierung von ERK und folglich eine Aktivierung oder Deaktivierung der ERK-vermittelten Signalkaskaden in HBMEC konnte jedoch im Laufe …
-
Virulence potential and host response to Cronobacter sakazakii
… and invasion of mammalian intestinal and brain cells by these strains were evaluated using colorectal adenocarcinoma epithelial cells (Caco-2), human brain microvascular endothelial cells (HBMEC), and rat brain capillary endothelial (rBCEC4) cell lines. Furthermore, the ability of the …
-
Exploration of a doxorubicin-polymer conjugate in lipid-polymer hybrid nanoparticle drug delivery
… lies in using Dox- PLGA LPNs to cross the blood-brain barrier (BBB). The incorporation of Dox-PLGA is hypothesized to have a protective effect on the BBB as its slow release profile will prevent drug from harming the BBB. Using induced pluripotent stem cells differentiated to human brain …
-
Examining Cellular Interactions and Response to Chemotherapy in The Glioblastoma Perivascular Niche
… (GBM) is the most deadly and common form of brain cancer and is responsible for over 50% of adult brain tumors. A specific region within the GBM environment is known as the perivascular niche (PVN). We have designed a 3D in vitro model of the PVN comprised of either collagen Type 1 or …
-
Optimizing the Extraction of Phenolic Antioxidant Compounds from Peanut Skins
… peroxide (H₂O₂)-induced oxidative stress in human brain microvascular endothelial cells (HBMEC) and the effect of PSE on lipid oxidation in commercial peanut butter were also evaluated. In the SLE method, EtOH was found to be the most efficient extraction solvent followed by MeOH, water and …
-
ORGANOIDS AS TOOLS TO STUDY BRAIN DEVELOPMENT AND DISEASE
Human brain organoids (ORG) are a widely used in vitro model that contribute to our knowledge about the biology and pathophysiology of the nervous central system (CNS). They are 3D multicellular clusters that mimic the cytoarchitecture and the developmental pathways that occur in vivo. The most …
-
Characterization and Application of Peanut Root Extracts
Lipid oxidation is one of the leading causes of food quality degradation. Manufacturers typically add antioxidants or purge a product's package of oxygen to inhibit oxidation and the resulting off-flavors. Synthetic antioxidants (e.g. BHT, BHA) and some natural antioxidants (e.g. α-tocopherol) have …
-
Interaktion von Listeria monocytogenes mit Endothelzellen
Listeria monocytogenes überwindet endotheliale Barrieren, um eine Meningitis oder Encephalitis auszulösen. Das Hindurchtreten durch diese Barriere könnte über die Invasion von Endothelzellen durch Listerien aus dem Blut und anschließender Freisetzung der Bakterien ins Gehirn erfolgen. In den ersten …