Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 488 for “"human brain"”.
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Structure-function relationships in human brain development
… for generating mechanistic explanations of brain function. In this thesis, I first establish a proof-of-principle that neuroanatomical connectivity, as measured with diffusion weighted imaging (DWI), can be used to calculate connectional fingerprints that are sufficient to delineate fine …
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Selectivity for Movement Direction in the Human Brain
… movement direction in many regions of the monkey brain. In my thesis, I investigated which areas in the human brain show directional selectivity. Moreover, I measured to what extent directional selective regions are sensitive to changes in other movement parameters, like the type of motor act and …
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Connecting Deep Learning Models to the Human Brain
… models that integrate vision and language with human brain processing. These models have shown remarkable advancements in tasks such as object recognition, scene classification, and language processing, achieving near-human accuracy in some cases. This raises intriguing questions about how …
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Scalable Subcellular Resolution Mapping of the Human Brain
… as molecular details of individual cells in the human nervous system, at the microscopic scale and human brain-wide scale. This thesis aims to develop various chemical and computational technologies as part of a fully integrated technology platform for simultaneously extracting spatial, …
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Monoaminergic Signaling in the Human Brain: New Insights
… to neural computations throughout the forebrain, influencing attention, learning and decision-making. However, resolving these monoaminergic signals at physiologically and behaviorally relevant spatiotemporal scales in the human brain have been constrained by limitations of available …
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Modeling The Functional Human Brain: A Network-Based Approach
… practice in neuroscience has been to examine the brain in terms of isolated components extracted from images. However, more recent trends have moved towards the examination of the entire brain in order to observe the complete topology and to capture emergent behavior not present at the component …
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Subject-Specificity of SC-FC in the Human Brain
The human brain can be depicted as a connectome, which describes how regions are connected amongst one another. Structural connectivity (SC) describes how physical pathways link areas of the brain, whereby functional connectivity (FC) describes the temporal relationships of neural activity between …
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From perceptual to semantic representations in the human brain
Humans are capable of recognizing a myriad of objects in everyday life. To do that, they have evolved the ability to detect their commonalities and differences, moving from perceptual details to construct more abstract representations that we call concepts, which span entire categories (such as the …
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Development Of Human Brain Network Architecture Underlying Executive Function
… to adulthood is characterized by refinements in brain structure and function that support the dynamic control of attention and goal-directed behavior. One broad domain of cognition that undergoes particularly protracted development is executive function, which encompasses diverse cognitive …
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High-Resolution Diffusion Tensor Imaging and Human Brain Connectivity
… has emerged as a unique method to characterize brain tissue microstructure non-invasively. DTI typically provides the ability to study white matter structure with a standard voxel resolution of 8μL over imaging field-of-views of the extent of the human brain. As such, it has long been …
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Frequency-Domain Near-Infrared Spectroscopy in the Human Brain
Monitoring brain tissue oxygen supply, demand, delivery and consumption can be achieved by quantifying the absolute values of oxy- and deoxy-hemoglobin and how these quantities change over time during rest, functional activation, pathology, and disease. My dissertation describes the development, …
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Carbon and Deuterium MRI studies of human brain metabolism
Metabolic changes to the brain can be due to brain disease causing impaired functioning. Imaging of the metabolic processes is an emerging area of research that can allow for greater understanding of the brain disease whilst offering clinical potential for improved diagnosis. Hyperpolarized (HP) …
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Inhibitory mechanisms for visual learning in the human brain
… between indistinguishable targets. As the human brain is trained on this type of visual tasks, we observe changes in its function that correspond to improved performance. We use functional brain imaging, to measure learning-dependent modulations of brain activation and investigate the …
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Algorithms for enhanced spatiotemporal imaging of human brain function
Studies of human brain function require technologies to non-invasively image neuronal dynamics with high spatiotemporal resolution. The electroencephalogram (EEG) and magnetoencephalogram (MEG) measure neuronal activity with high temporal resolution, and provide clinically accessible signatures of …
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The Role of Aerobic Glycolysis in the Resting Human Brain
The human brain accounts for 2% of total body weight, though it consumes 20% of the body's energy supply. Most of this energy is provided by the complete oxidation of glucose to carbon dioxide and water, though some fraction of glucose undergoes aerobic glycolysis without concomitant oxidative …
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Molecular Mechanisms of Opioid Use Disorder in Human Brain Models
… of long-term exposure to opioid drugs in human brain is still unclear, and human-centered translational models are necessary to discern the human cell type-specific effects of OUD.</p> <p>Using postmortem brain Brodmann area 9 (BA9) from the UTHealth Brain Collection for Research on …
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Resource allocation of the human brain : a competitive equilibrium approach
… study the resource allocation of a functioning brain is proposed. The mechanism is based on the theory of competitive equilibrium (CE), where users (cortical areas of the brain) are competing for a finite resource such as oxygenated blood. Concepts of CE are mathematically adjusted to be used …
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The Representation Of Numerosity In The Human Brain And Machines
… survival and reproductive success. In humans, it may serve an additional purpose by providing a start-up kit for the acquisition of symbolic numbers, thus making it a potential focus for mathematics education and intervention strategies. Behavioral, neurophysiological, and neuroimaging …
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Exploring the role of autophagy in shaping human brain development
Contains fulltext : 322721.pdf (Publisher’s version ) (Open Access)
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Visual Analytics and Interactive Machine Learning for Human Brain Data
… focuses on applying visualization techniques on human brain data for data exploration, quality control, and hypothesis discovery. It mainly consists of two parts: multi-modal data visualization and interactive machine learning. For multi-modal data visualization, a major challenge is how to …
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