Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"human ailments"”.
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Structure-activity relationships of PAI-1 inhibitors
… to increase our understanding of various human ailments with which high levels of PAI-1 have been associated, including diabetes, stroke, and atherosclerosis. Previous accounts have reported the synthesis of inhibitors that bind to PAI-1 with a low affinity, inhibit the serpin plasma …
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Generation of novel small molecules as inhibitors of plasminogen activator inhibitor-1
… clots. PAI-1 also exhibits effects on various human ailments including atherosclerosis, stroke and diabetes, with which high levels of PAI-1 have been associated. The goal of this research study is to design novel, potent, and specific small molecule inhibitors of PAI-1. The structural …
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Isolation and characterization of antidiabetic constituents of Bridelia Micrantha
… healers in the treatment of different human ailments including diabetes, gastrointestinal ailments, joint aches, cough, conjunctivitis, skin problems and malaria. Previous studies have demonstrated the antidiabetic activities of B. micrantha crude extracts in in vivo studies. However, …
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Engineering Secreted Proteins for Gene Transfer and DNA Vaccination
… become a promising way of alleviating incurable human ailments, its concept emerging as the ultimate therapy for many infectious and genetic diseases. Two important aspects of the development of successful gene therapy protocols are the ability to monitor gene transfer readily, and the …
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Phytochemical and cytotoxicity studies on Arbutus pavarii, Asphodelus aestivus, Juniperus phoenicea and Ruta chalepensis growing in Libya
… medicine for the treatment of various human ailments, including both tumours and cancers. The cytotoxic activity of the n-hexane, dichloromethane (DCM) and methanol (MeOH) extracts of these plants were assessed against five human tumour cell lines: urinary bladder cancer [EJ-138], liver …
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Expanding the versatility of aminoquinoline organometallic complexes as anticancer and antibacterial agents
… types, bacterial infections as well as other human ailments. Increasing attention has been given to the development of metal complexes as photosensitisers based on their attractive photophysical and biological properties. The aminoquinoline motif has been recognised as a remarkably versatile …