Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"human adenovirus"”.
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Characterization of the Human Adenovirus 19a E3/49K Protein
Human adenoviruses (Ads) cause a variety of acute diseases but also establish persistent infections. Ads have evolved a number of mechanisms to evade the host immune response that seem to facilitate virus replication and transmission in vivo. Interestingly, one Ad transcription unit, the early …
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Kinetics and Mechanisms of Human Adenovirus 2 Inactivation With UV and Chlorine
… to potable water. Of particular interest are adenoviruses, which are on the CCL2 issued by the EPA. Unfortunately, the recently-adopted method of irradiation by ultraviolet (UV) light is largely ineffective against adenoviruses. Research is therefore required to find whether any of the other …
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The Interaction of the Human Adenovirus E1A Protein with the Human DREF Transcription Factor
The human adenovirus (HAdV) E1A protein is the first protein produced post-HAdV infection, and serves two main functions. The first is to modulate host and viral transcription. The second is to induce host cell cycle progression to S phase, to promote an optimal environment for viral replication. …
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Comparative mechanistic study of Coxsackievirus B5 and Human Adenovirus Serotype 2 inactivation by chlorine
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
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Inactivation mechanisms of adenovirus from exposure to polychromatic ultraviolet light irradiation
… regulations on disinfection byproduct formation. Human adenovirus (HAdV) is found in water sources around the world and can cause respiratory, urinary, gastrointestinal, and eye infections. HAdV has emerged as a waterborne pathogen of concern due to its resilience against UV light inactivation. …
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Determination of the prevalence and diversity of viral gastroenteritis infections and secretor status in the elderly population of the Tshwane region in South Africa
… testing for norovirus GI and GII, rotavirus, human adenovirus, human astrovirus and sapovirus. Careful analysis of the real-time (RT)-PCR amplification plots and export data identified 50 viruses in 40 patient specimens. Seven norovirus GI/GII dual-infections were observed and three …
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Demonstration of new subtypes of adenovirus 7 in South Africa, and probing oesophageal carcinoma cell lines for evidence of adenovirus or of other oncogenic viruses
… carried out in 2 parts: 1. Genome analysis of human adenovirus species 7; 2. Search for a possible viral aetiology in oesophageal carcinoma. Sixteen laboratory isolates of adenovirus species 7, isolated in South Africa between 1975 and 1986, were characterized by restriction endonuclease …
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Inactivation of adenovirus serotype 41 with monochloramine
… caused by a lack of safe water and sanitation. Human Adenovirus (HAdV) is a viral pathogen that persists in contaminated water and is commonly found to cause diarrhea worldwide. The United States Environmental Protection Agency has included HAdV in the Drinking Water Contaminant Candidate List 4 …
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Kinetics and mechanisms of bacteriophage PR772 inactivation by monochloramine
… for environmental engineers and researchers. Human Adenovirus (HAdV) is a pathogen listed in the Contaminant Candidate List 4 of the United States Environmental Protection Agency. HAdV is highly resistant to monochloramine, a common drinking water disinfectant used in the United States and …
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Investigation of the mechanisms of ozone-mediated viral inactivation
… A strain (H1N1) A/WS/33] and non-enveloped [human adenovirus type2 (Ad2)] viruses. Plaque reduction and suspension-infection viral antigen assays were used to determine inactivation kinetics. After ozonation, HSV-1 and VSV lost up to 6 log10 infectious particles in 15 min, while VAC and …
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Role of viral vectors in candidate HIV vaccine-induced immune responses
… while multiple trials utilizing the recombinant human adenovirus vector Ad5 either demonstrated no efficacy or transiently increased the risk of HIV infection in vaccine recipients with pre-existing immunity to the Ad5 vector. The aim of this dissertation is to help fill the gap in our knowledge …
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Mucosal and systemic immune responses induced by immunisation of cotton rats with recombinant adenoviruses
… and replication-competent recombinant human adenovirus type 5 vectors efficiently expressed the glycoprotein D (gD) or the transmembrane anchor truncated gD (tgD) of bovine herpesvirus type 1 (BHV-1) in vitro. To facilitate the evaluation of the efficacy of immunisation with these …
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The role of Ad-36 and its E4orf-1 protein in modulating glycemic control
… or lifestyle changes may be highly useful. Human adenovirus Ad36 offers such a model. Ad36 improves glycemic control in chow-fed mice or rats and attenuates diabetes and hepatic steatosis in high fat(HF)-fed mice, despite the HF intake and without reducing adiposity. In human adults, natural …
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