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Showing 1 to 3 of 3 for “"hspb5"”.

  1. Disease-modifying effects of human small heat shock proteins in zebrafish models of neurodegeneration

    … zebrafish line ubiquitously expressing human HSPB5. I demonstrate that overexpression of HSPB5 in the pan-neuronal A152T tau line results in reduced levels of hyperphosphorylated and insoluble tau. Additionally, a synthetic HSPB5 peptide similarly ameliorated morphological phenotypes by …

    cambridge Repository record for Disease-modifying effects of human small heat shock proteins in zebrafish models of neurodegeneration (opens in a new tab)

  2. The sHsp expression signature in the brain and modulation in models of chronic neurodegeneration

    … specific expression pattern for HspB5 (?Bcrystallin).<br/>HspB1 (Hsp25) and HspB8 (Hsp22) demonstrated overlapping expression in the<br/>lateral and dorsal ventricles of the brain, as well as expression in a distinct set of motor<br/>neurons in the ventral horn of the spinal cord. …

    soton Repository record for The sHsp expression signature in the brain and modulation in models of chronic neurodegeneration (opens in a new tab)