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Showing 1 to 20 of 121 for “"hsp"”.
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Formas de CRISP-3, HSP-1 e HSP-2 como candidatas a marcadores de congelabilidade do sêmen de garanhões da raça Mangalarga Marchador
… protéico identificou-se 5 famílias de proteínas (HSP-1, HSP-2, CRISP-3, Calecreína e Albumina sérica). Destas famílias, algumas proteínas se apresentaram com diferenças em abundância (p<0,05) entre os grupos estudados, em que quatro destas podem ser consideradas possíveis candidatas a marcadores …
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The Cystic Fibrosis Transmembrane Conductance Regulator: Regulation by HSP-90
… relevant association exists between CFTR and Hsp90. In testing this hypothesis, (a) the association of CFTR and Hsp90 is confirmed via crosslinking and immunoprecipitation of CFTR from stably transfected HEK-293 cells, electrophoretic separation of cross-linked proteins, and protein …
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Biolistic-mediated transformation of Eragrostis Curvula with the HSP 12 gene
… of E. curvula with Saccharomyces cerevisiae Hsp 12 gene using biolistic-mediated transformation. Firstly, a tissue culture protocol was established for E. curvula that was suitable for transformation studies. Although this species has been previously regenerated in vitro using inflorescence …
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A Process Evaluation of the Academic Component of the Hope Scholars Programme (HSP)
The Hope Scholars Programme (HSP) is an after-school programme implemented by the South African Education and Environment Project (SAEP) in Cape Town, South Africa. After-school programmes (ASPs) are widely described as programmes that are implemented independently of the school day and are aimed …
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Investigation of Interaction between heat shock protein 70.14 (Hsp 70.14) and RBBP6 RING finger domain
… therapeutic potential of heat shock proteins (Hsps) as an alternative intervention against cancer because of their ever-presence in the pathology of different facets of cancer development. Studies have shown that tumour cells require Hsp chaperonin activities for survival and proliferation than …
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Testing roles of Hereditary Spastic Paraplegia (HSP) proteins in organization of axonal endoplasmic reticulum (ER) and ER-mitochondria contacts
The Hereditary Spastic Paraplegias (HSPs) are a group of genetically heterogeneous, neurodegenerative and neurodevelopmental diseases characterised by spasticity and lower limb weaknesses. Some known causative genes imply the importance of endoplasmic reticulum (ER) function and morphogenesis in …
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Genotoxic effects of a novel form of Gold Nanoparticles loaded with Hesperidin on head and neck cancer lymphocytes compared to effects from healthy control lymphocytes and Squamous cell Carcinoma of Maxillary sinus
… (AuNPs) conjugated with hesperidin (Hsp) as a targeted drug delivery system. AuNPs are ideal for loading different drugs and delivering them to targets sites due to their stability, small size, substantial surface area, non-cytotoxic and inert nature. Hsp is a naturally occurring …
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Genotoxic effects of a novel form of Gold Nanoparticles loaded with Hesperidin on head and neck cancer lymphocytes compared to effects from healthy control lymphocytes and Squamous cell Carcinoma of Maxillary sinus
… (AuNPs) conjugated with hesperidin (Hsp) as a targeted drug delivery system. AuNPs are ideal for loading different drugs and delivering them to targets sites due to their stability, small size, substantial surface area, non-cytotoxic and inert nature. Hsp is a naturally occurring …
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The isolation and characterization of heat shock protein Hsp12 in Lipomyces starkeyi
The stress response protein Hsp 12 is induced in S. cerevisiae cells upon exposure to salt stress, heat shock, ethanol, and upon entry to stationary phase (Mtwisha et aI., 1998). In this study, the occurrence of proteins related to Hsp12 was investigated in a number of yeasts (namely, Saccharomyces …
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Stress response genes in the human proximal tubules
The heat shock proteins (hsps) are believed to provide protection against a variety of insults such as elevated temperature, heavy metals and chemical agents. The goal of this study was to determine if the immortalized HK-2 human proximal tubule cell line could provide a model system to study the …
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Heat shock protein 27 inhibition of the caspase cascade in human breast cancer cells
… is an over-expression of Heat Shock Protein 27 (HSP27), the cell does not obey the death signals that it receives. In this study, the molecular mechanism for the HSP 27 inhibition of the caspase cascade is described in human breast cancer cells that were engineered to constitutively express HSP …
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The Heat Shock Proteins of Maize: Their Induction, Cellular Location, and Potential Function
… to 40(DEGREES)C, a set of "heat shock proteins" (hsp) is induced in maize. This response is presumed to be homeostatic, although the precise function of the proteins is unknown. This work investigates the regulation of hsp synthesis and potential physiological roles of the hsp by determining their …
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The Use of Solubility Parameters to Select Membrane Materials for Pervaporation of Organic Mixtures
… industry uses Hansen solubility parameters (HSP) to indicate polymer solubility. The potential of this method to predict solvent-polymer affinity was investigated for screening potential membrane materials for the pervaporation of a model solution containing linalool and linalyl acetate …
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Correlation of Polymer Performance and Hansen Solubility Parameters
… to research into Hansen solubility parameters (HSP) and whether these could be used as performance predictive tools. Since HSP of polymers cannot be directly measured, Group Contribution Theory (GCT) had to be employed to estimate polymer HSP.</p> <p>It was determined that HSP is not as good of …
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Visualizing Roles of Spastic Paraplegia Proteins in Organizing Axonal ER in Live Drosophila
… disease, hereditary spastic paraplegia (HSP). However, the extent and mechanisms by which HSP proteins contribute to axonal ER organization and dynamics are unclear. To understand these mechanisms, there is a need to visualize axonal ER in wild-type and mutant live axons. I have therefore …
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Towards the cloning of the human heat shock protein twenty-seven multigene family
… members of the human heat shock protein 27 (hsp 27) multigene family. Genomic DNA was obtained from human A549 lung cancer cells. Colony hybridization and the Polymerase chain reaction identified the hsp 27 genes. Positive clones were subcloned into pGEM-3Z. The DNA sequence information for …
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Molekulare Charakterisierung von ZFYVE27 und Identifizierung von Deletionen in SPG4
Die hereditären spastischen Paraplegien (HSP) sind eine klinisch und genetisch heterogene Gruppe erblicher neurodegenerativer Erkrankungen, welche durch eine progrediente spastische Paraparese und Hyperreflexie der unteren Extremitäten gekennzeichnet sind. Sie können autosomal-dominant, autosomal …
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Molekulare Charakterisierung des COPS5-Gens und seines Genproduktes als Kandidat für die Spastische Spinalparalyse
Die hereditären spastischen Paraplegien (HSP) bilden eine klinisch und genetisch heterogene Gruppe neurodegenerativer Erkrankungen. Das Vererbungsmuster folgt autosomal-dominaten (AD), autosomal-rezessiven (AR) und X-chrosomalen (X) Erbgängen. Eine besondere Bedeutung kommt dem SPG4-Gen mit seinem …
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Yeast cell wall proteomics: a tale of two proteins.
… proteins were found, phosphoglycerate mutase and Hsp 12. Studies on these proteins are reported in chapters 2 (phosphoglycerate mutase) and chapter 3 (Hsp 12).
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