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Showing 1 to 2 of 2 for “"hot melt granulation"”.
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Novel Carbopol-Wax Blends for Controlled Release Oral Dosage Forms
… processing difficulties of carbopol using hot melt granulation process and to develop sustained release oral formulations of a basic (Propranolol HCl) and an acidic drug (Glipizide).</p> <p>Hot melt granulation was used to prepare free-flowing, directly compressible carbopol-wax blends. …
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Optimization of granule size and tablet properties in a twin screw granulator: the influence of process and formulation parameters
… and other associated processing costs in wet granulation is a benefit of melt granulation. However, twin screw hot melt granulation is rarely applied in most industries. This work details the product characteristics and optimization from melt granulation of the model materials, calcium …