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Showing 1 to 2 of 2 for “"host transcriptional responses"”.

  1. The Landscape of Host Transcriptional Response Programs Commonly Perturbed by Infectious Pathogens: Towards Host-Oriented Broad-Spectrum Drug

    … and discovery of new anti-infective drugs. Host-Oriented Broad-Spectrum (HOBS) treatments have the promising potential to alleviate these problems. The HOBS treatment paradigm focuses on finding drug targets in human host that are simultaneously effective against a wide variety of infectious …

    vt Repository record for The Landscape of Host Transcriptional Response Programs Commonly Perturbed by Infectious Pathogens: Towards Host-Oriented Broad-Spectrum Drug (opens in a new tab)

  2. Influenza a virus gene expression heterogeneity regulates viral superinfection potential and host innate antiviral response

    … influences viral superinfection and host innate antiviral response. To initiate productive infection, multiple SIPs must co-infect one cell to achieve complementation. Within a certain MOI range, increasing the abundance of SIPs in a viral population increases the percentage of …

    uiuc Repository record for Influenza a virus gene expression heterogeneity regulates viral superinfection potential and host innate antiviral response (opens in a new tab)