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Showing 1 to 2 of 2 for “"host cell impurities"”.

  1. A multifaceted approach towards advancing the sterile filtration of therapeutic viruses

    … virus during sterile filtration, the effect of host cell impurities on filtration performance was investigated. This revealed that small amounts of host cell protein are a major factor in both membrane fouling and reduced virus yield, and that there is a synergistic effect between the virus and …

    mcmaster Repository record for A multifaceted approach towards advancing the sterile filtration of therapeutic viruses (opens in a new tab)

  2. Monoclonal Antibody Expression and Novel Purification in Nicotiana benthamiana

    … an UF/DF step, a precipitation of native impurities step using a charged polymer, hydrophobic interaction chromatography and hydrophobic charge induction chromatography. The yield of this modified process was 19.0%. This process compared favorably with Protein A due to the fact that even …

    vt Repository record for Monoclonal Antibody Expression and Novel Purification in Nicotiana benthamiana (opens in a new tab)