Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"hormone response"”.
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Identification of juvenile hormone response genes in newly emerged female Aedes aegypti
Juvenile hormone (JH) plays pivotal roles in the development and reproduction of insects. Efforts to characterize the mechanisms of JH regulation are complicated due to JH pathways often being intertwined with those of 20-hydroxyecdysone (20E). Upon adult emergence, female Aedes aegypti enter a …
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Effects of periconceptional undernutrition and twinning on ovine pregnancy
… showed decreased pituitary adrenocorticotropin hormone response to direct stimulation but increased adrenal response to decreased cortisol negative feedback. Twin fetuses grew more slowly in late gestation than singletons. Twins also had a smaller insulin response to arginine and a greater …
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Developmental Characterization of Cara Mitad: A Drosophila Nuclear Receptor Co-Regulator
<p>In insects and vertebrates, hormone titers drive cellular proliferation and differentiation events that guide proper development. Nuclear receptors (NR) respond to these hormone signals by activating cascades of gene expression, along with coregulator protein complexes. In Drosophila …
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Influence of Body Mass Index on Growth Hormone Responses to Classic Provocative Tests in Children with Short Stature
Objective: Growth hormone (GH) secretion is regulated by physiological parameters. Obesity is associated with diminished spontaneous and stimulated GH secretion. The aim of this study was to assess the influence of BMI on growth hormone response to provocative testing in children with short …
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Thyroid Status in Exercising Horses and Laminitic Ponies
… immunoassay (EIA) for measuring equine thyroid hormones and development and assessment of a thyrotropin releasing hormone (TRH) response test. Our data indicated that EIA is an acceptable method for the measurement of total (T) and free (F) thyroxine (T4) and triiodothyronine (T3) in equine …
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Cloning and Estrogen Regulation of the Retinol Binding Protein Messenger-Rna of Xenopus Laevis
… is studying the mechanisms by which the hormone, estrogen, regulates gene expression in the frog, Xenopus laevis. In this thesis, I described the isolation of a full length cDNA clone for an estrogen induced mRNA isolated from the liver of Xenopus laevis. By DNA sequencing and subsequent …
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Site-specific phosphorylation of histone H1 associated with cell cycle progression and transcription
… rDNA promoters and is rapidly induced at steroid hormone response elements by hormone treatment. Our results imply that site-specific interphase H1 phosphorylation facilitates transcription by RNA polymerases I and II, and has an unanticipated function in ribosome biogenesis and the control of …
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Illuminating epithelial-stromal communication using engineered synthetic matrix microenvironments
… undergoes monthly cyclic remodeling via hormone-mediated growth, immune cell recruitment and proteolytic breakdown. Hormone response disruption has been associated with numerous endometrial pathologies, including endometriosis, adenomyosis, and infertility, which impacts upwards of 10% of …
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Regulation of SRC-3 localization and dynamics by phosphorylation during ERα-dependent transcriptional activation
… to cis-regulatory enhancers elements, termed hormone response elements (HREs), in a specific subset of genes. Regulation by these factors involves either the recruitment of coactivators or corepressors and direct interaction with the basal transcriptional machinery (1). Hormone-activated …
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Hormonal and metabolic responses to opioid antagonism during dynamic exercise : influence of exercise intensity
… peptides in substrate utilization and hormonal responses to exercise, eight trained cyclists completed two exercise trials at each of two distinct intensity/duration combinations. Briefly, cyclists completed two trials at 70% VO2max for 90 minutes and two trials at 90% VO2max until exhaustion. …
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Mechanisms underlying lipotoxicity and glucotoxicity in pancreatic islets
… (FFA) or glucose negatively modulates islet hormone release, the identities of signals mediating these effects are not yet fully clarified. The overall objective of this study was to investigate signal transduction pathways involved in FFA- and glucose-exerted effects on beta-cell function …
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Interactions of Steroid Hormone Receptors With Coactivators and DNA
II Steroid hormone receptors (HR) activate gene transcription through binding to ligands, locating specific hormone response elements (HREs) on DNA, recruiting coactivators and then chromatin remodeling complexes and ultimately the basal transcription machinery. In vivo data suggests that the …
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Circadian regulation and phytohormone responses of cytochrome P450 monooxygenase genes in Arabidopsis
… growth and development are regulated by both hormone and circadian signaling pathways. The growing number of signaling molecules whose syntheses are circadian-regulated (e.g. jasmonic acid, auxin) and the time-of-day-specific transcripts of cytochrome P450 monooxygenases (P450s) involved in …
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SPCA and regucalcin: expression, activity and regulation in Ca2+ homeostasis
… pathway and ability to influence vasopressin response in VSMCs. Bis-phenol has now been quantitatively shown to be a potent and specific inhibitor of SPCA, giving it great potential to be used as a pharmacological tool for future research on this Ca\(^{2+}\)-ATPase. For RGN, it appears …
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Studies on the Granule-Moving System of Melanocytes of Fundulus Heteroclitus
… and long distance intracellular migrations in response to hormones. These movements have been studied and a theory of the granule moving system has been proposed: The granules are in a structured continuum which expands and contracts to move them; the state of the continuum is the resultant of …
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Define The Epigenetic Profiles and Subtype-Specific Genes of Breast Cancer
… breast cancer. These 5 subtypes correlate with hormone response, patient prognosis, and response to therapy. Although steady state gene expression patterns have been explored using expression microarrays, very little is known about the initial, disease-driving transcriptional changes in these …
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Transcriptomic study of evolution and gene expression in diploid and allotetraploid glycine subgenus glycine
… cis-regulatory motifs related to light and / or hormone response. Taken together, this would suggest that expression sub-functionalization achieved through differential pattern of homeolog expression bias may have an important role in the increase adaptability of allotetraploid species to a wider …
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Relationships of gastric emptying with glycaemia, insulin secretion and the incretin effect in health and type 2 diabetes
… relationships between gastric emptying, incretin hormones (GIP and GLP-1) and postprandial glycaemic and insulinaemic responses in health and type 2 diabetes. Key themes relate to: 1) Evaluation of the relationships of ‘early’ and ‘late’ glycaemic responses with gastric emptying in subjects with …