Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"hormone Treatment"”.
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Cyborg Butterflies, Liminal Medicine: Thyroid Hormone Treatment, 1890-1970
In this thesis, I develop a history of thyroid hormone treatment (THT) that centers on the bodies of animals and women between 1890 and 1970. This history contextualizes the current debate between two forms of THT, desiccated and synthetic. Drawing on the discourses present in biomedical journals, …
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Effects of long-term hormone treatment on cognitive behavior and the structure of the medial prefrontal cortex during aging in female rats
Although previous research has indicated that hormone replacement therapy benefits memory in menopausal women, several newer studies have shown no effect or detrimental effects. These inconsistencies emphasize the need to evaluate the role of hormones in protecting against agerelated cognitive …
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Regulation of elements of the thyroid hormone and corticosteroid systems by stress, hormone treatment, and atrazine during ontogeny of red drum (Sciaenops ocellatus)
… examined the ontogeny of elements of the thyroid hormone (TH) and corticosteroid (CS) systems in red drum (Sciaenops ocellatus). Basal cortisol production was first detected 3 days post-hatch (DPH) and a cortisol stress response was present from 6 DPH forward. Changes in steroidogenic enzyme mRNA …
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THE METABOLIC EFFECTS OF DIET-INDUCED OBESITY AND GROWTH HORMONE TREATMENT IN LONG-LIVED MICE WITH ALTERED INSULIN AND INSULIN-LIKE GROWTH FACTOR -1 SIGNALING
… EFFECTS OF DIET-INDUCED OBESITY AND GROWTH HORMONE TREATMENT IN LONG-LIVED MICE WITH ALTERED INSULIN AND INSULIN-LIKE GROWTH FACTOR -1 SIGNALING MAJOR PROFESSOR: Dr. Andrzej Bartke It is well established that high calorie diets providing mostly fat and simple carbohydrates as nutrients …
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Conjugated Estrogen Receptor Probes: An Evaluation of Fluorophores, Photolabile Groups, Estrogenic Ligands, and the Nature of the Attaching Chain
… in breast tumors, and their responsiveness to hormone therapy. However, the correlation is not perfect; about 40% of women with measurable tumor receptor levels do not respond to hormone treatment. The work described herein was undertaken in order to improve the predictability of hormone …
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The association between oestrogen, memory, cognition and mood in a male-to-female transsexual population
Research has demonstrated that gonadal hormones, including oestrogen, can influence memory and cognitive tasks that show sex differences in animals and humans. Beneficial effects of oestrogen on mood have also been reported in postmenopausal women in association with Oestrogen Replacement Therapy …
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Regulation of LKB1-STRAD-MO25 Complex Expression and Activation of AMPK in Skeletal Muscle by Thyroid Hormone
… is a research target for the pharmaceutical treatment and prevention of type 2 diabetes. The expression of all of the isoforms of the subunits of AMPK and AMPK activity are increased in skeletal muscle tissue of hyperthyroid rats. Activity of AMPK is regulated by an upstream kinase (AMPKK). …
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Some in vivo effects of triiodothyronine on purine nucleotide synthesis
… in the levels of total adenine or guanine. Hormone treatment stimulated the rate of incorporation of glycine into AMP and NAD<sup>+</sup> within 1.5 hours. The magnitude of the observed increases in specific activity of AMP and NAD<sup>+</sup> were dependent upon the relative timing of …
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Effects of estrogen and progesterone on tolerance to thermal stress
… control animals and those treated with P; All treatment groups had a significantly lower tail skin temperature as compared to the control animals. The rise in Tre in E and EP treated rats did not appear to result from an increase in metabolism since the rates of oxygen consumption did not …
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Transcatheter Arterial Embolization of Prostate in Hormone Induced Canine Prostate Hyperplasia
… intervention among elderly men. Currently, main treatment modalities are medication and transurethral resection of the prostate (TURP) which is considered as the gold standard for the surgical management of symptomatic BPH. A number of minimally invasive techniques for treatment of BPH have …
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EXERCISE IS NEUROPROTECTIVE TO MOTONEURON DENDRITES FOLLOWING PARTIAL MOTONEURON DEPLETION VIA A MECHANISM DEPENDENT ON ANDROGEN RECEPTORS AT THE TARGET MUSCLE
… in nearby surviving motoneurons, and that treatment with testosterone attenuates these structural and functional deficits. In this dissertation, I establish that exercise following partial motoneuron depletion is similarly neuroprotective to motoneurons, via a mechanism that requires …
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The effect of ACTH and progesterone on semen characteristics, blood hormones and testicular histology in the bull
… The endocrine response during and following hormone administration was monitored to determine if there was an association between the appearance of spermatozoal abnormalities and plasma hormone changes. During Experiment 1, one 7-yr-old and two yearling Holstein bulls were injected with 200 …
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Effects of Estrogens on Astrocytes Exposed to Stressors
<p>Hormone replacement therapy (HRT), used by many women to alleviate menopausal symptoms such as hot flashes and mood swings, is often a combination of horomones such as estrogens, progesterone, and conjugated equine estrogens (CEE), extracted from the urine of pregnant mares. Previous studies …
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Investigating luteinizing hormone receptor signal transduction using the cyclic AMP reporter ICUE1
… tumors. Assay of cAMP levels in response to hormone treatment is usually used to demonstrate LH receptor activation and has historically relied on biochemical methods. ICUEl is an Epac-based cAMP reporter which undergoes conformational changes after binding cAMP. Unlike traditional …
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Retinoic Acid Regulation of Thyroid Hormone Action in Bone Cells
<p>Retinoic acid and thyroid hormone are known to play key roles in the regulation of endochondral ossification. However, the issue of whether these two hormones interact with each other to regulate bone functions remains to be established. We investigated how thyroid hormone and retinoic acid …
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Hypothalamic beta-endorphin, body weight, and food intake in ovarian steroid treated rats
… weight changes occurring with ovarian steroid treatments, 80 adult female Sprague-Dawley rats were ovariectomized and allowed to recover for 7 days. Four treatment groups of 20 each were subjected to daily injections for 14 days with A) oil, B) β-estradiol benzoate (2µg), C) β-estradiol …
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Site-specific phosphorylation of histone H1 associated with cell cycle progression and transcription
… rDNA promoters and is rapidly induced at steroid hormone response elements by hormone treatment. Our results imply that site-specific interphase H1 phosphorylation facilitates transcription by RNA polymerases I and II, and has an unanticipated function in ribosome biogenesis and the control of …
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Fundulus grandis Response to Exogenous LH Injection.
… of the ovary. Injections of ovine luteinizing hormone (o-LH) were made at different times of the day (early, midday, and late) as well as during times of differing reproductive condition (different times of the year). Additionally, a dose response curve to the o-LH was determined on both sexes. …
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Thyroid Hormone Effects on Sertoli Cell Gene Expression in the Rat
Thyroid hormones, along with other hormones such as follicle stimulating hormone (FSH), regulate neonatal Sertoli cell development. It was not clear however, if all of the changes seen in Sertoli cell development during hypothyroidism represent direct effects of thyroid hormone deficiency on the …
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Altered estrogen receptor and transforming growth factor pathways in models of estrogen-autonomous and of antiestrogen-resistant MCF-7 human breast cancer cells
… cancer with antiestrogens, the most efficacious hormone treatment used clinically. We developed two models in the MCF-7 cell line, an estrogen receptor-positive human breast cancer cell line, to assess the relative importance of the estrogen receptor pathway and the transforming growth factor …
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