Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 129 for “"horizontal gene transfer"”.
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Understanding microbial communities through horizontal gene transfer
… the community assembly process under a serial transfer regime at a higher resolution and concluded that the diversity maintained is little affected by the complexity of the carbon source. Systematic variation of parameters in the regime demonstrated that diluting the initial inoculum has the …
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Factors that affect horizontal gene transfer in enteric bacteria
… environments through mutations or through horizontal gene transfer (HGT) of genetic material containing resistance genes. Conjugation machinery offers an efficient method for acquisition of AMR and virulence genes, which may be responsible for propelling the evolution of pathogenic …
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HORIZONTAL GENE TRANSFER (HGT) AND SPHAGNUM FALLAX: A PHYLOGENETIC LOOK INTO THE OCCURRENCE, PREVALENCE, AND IMPORTANCE OF HORIZONTAL GENE TRANSFER IN A BOG MOSS
Horizontal gene transfer (HGT) is a biological process that involves any transmission of genetic material that isn't vertical in nature. HGT occurs frequently between prokaryotes and plays a significant role in prokaryotic evolution. This process is also known to occur between symbiotic bacteria …
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Horizontal gene transfer as a cohesive force in microbial populations
… defined as groups of organisms with a shared gene pool in which adaptive genes can spread freely through natural selection. Ecology takes a less abstract view of populations and conceives of them as members of a single species that occupy the same geographical area. Among sexual eukaryotes, …
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Bacterial transport and horizontal gene transfer in subsurface: multiple-scale experimental studies
Horizontal gene transfer rapidly changes bacterial genetic repertoire and contributes to bacterial evolution. Natural transformation, one mechanism of horizontal gene transfer, is defined as the process by which bacterial cells successfully take up and incorporate extracellular DNA. The …
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Regulation of horizontal gene transfer by intercellular peptide signaling in Bacillus subtilis
Horizontal gene transfer plays an important role in bacterial evolution. Although acquisition of foreign DNA can be beneficial to cells, it can also be detrimental. Therefore, cells that possess mechanisms to regulate horizontal gene transfer likely have a competitive advantage. Similarly, several …
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Spatial dynamics of microbial populations driven by social interactions and horizontal gene transfer
… we found that interaction topologies and horizontal gene transfers drive the spatial structure formations of bacterial communities. Spatial interaction scales, growth rates and antibiotic selection forces are other modulators that affect the spatial structures. Our results confirm social …
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Improvements in codon usage analysis for a more detailed understanding of genome content and horizontal gene transfer
The genetic code has evolved with considerable elasticity, enabling most amino acids to be encoded by multiple synonymous codons. Genes can vary in their utilization of synonymous codons, and this provides a basis of comparison for studying the compositional histories and evolution of genomes. The …
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Phylogenetic Analysis Suggests Horizontal Gene Transfer Event Within the Mitis Group Within the Genus Streptococcus Involving L-Amino Oxidase In Streptococcus Oligofermentans
<p>This phylogenetic study was undertaken in order to provide further elucidation to evolutionary relationships within the genus streptococcus. The inhibition by Streptococcus oligofermentans of Streptococcus mutans is of particular interest. A comprehensive mechanism for this inhibition has been …
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Genome evolutionary studies of the Salmonella enterica serovars: implications for the dynamics of horizontal gene transfer, the pangenome concept, and bacterial and archaeal taxonomy
… microbes appear to be constantly subjected to gene gain and gene loss processes. The influence of gene gain, specifically through the process of horizontal gene transfer, appears to be so profound that the gene content amongst strains of a lineage may vary as much as 80%. However, the sources …
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The Effect of Select Biological and Environmental Factors on the Horizontal Gene Transfer and Functionality of the TOL Plasmid: A Case Study for Genetic Bioaugmentation
… Although in situ bioremediation processes generally offer more advantages than ex situ methods, there are concerns with the current in situ methods that limit their effectiveness. For example, a major concern in bioaugmentation is the effect of the addition of large quantities of …
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Two Problems in Computational Genomics
… genome alignment and the second is inferring horizontal gene transfer using posets. We define these two problems and present algorithmic approaches for solving them. For the whole genome alignment, we define alignment graphs for representing different evolutionary events, and define a scoring …
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Characterization of an exclusion mechanism in an integrative and conjugative element in Bacillus subtilis
Horizontal gene transfer is the acquisition of new genetic material that can confer novel phenotypes to bacteria and contribute to their evolution. Conjugation is an important mechanism of horizontal gene transfer that involves the direct transfer of DNA between two cells and is mediated by mobile …
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Fate of Antibiotic Resistance Genes During Anaerobic Digestion of Wastewater Solids
… resistant bacteria (ARBs), antibiotic resistance genes (ARGs), and the environment through discharge of treated effluent and land application of biosolids. Recent studies observing an apparent resuscitation of pathogens and pathogen indicators and the widening realization of the importance of …
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An experimental investigation into the mechanisms of bacterial evolution
… mechanisms of bacterial evolution — horizontal gene transfer and spontaneous mutation, in the bacterium <em>Escherichia coli</em> through novel experimental assays and mathematical simulations. First, I will develop a growth assay utilizing the quantitative polymerase chain reaction …
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Gene transfer agents promote survival and DNA repair during stationary phase for Caulobacter crescentus
Gene transfer agents (GTAs) are prophage-like entities found in many bacterial genomes that cannot propagate themselves and instead package ~5-15 kbp fragments of the host genome that can then be transferred to related recipient cells. Although suggested to facilitate horizontal gene transfer in …
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The innate immune response to Mycobacterium tuberculosis is dependent on strain lineage and on host population
… is strongly clonal, in the absence of horizontal gene transfer. Thus it is feasible that clonal lineages may exhibit particular phenotypic characteristics, which may, in turn, result in differences in virulence or influence their association with particular host populations. Indeed, the …
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THE ROLE OF SPATIAL SCALES IN BIOGEOGRAPHY AND EVOLUTION OF SOIL-BORNE STREPTOMYCES
… separation on Streptomyces community assembly, horizontal gene transfer events, and population differentiation. A combination of amplicon sequencing and comparative genome analyses show that dispersal limitation occurs at local, regional, and continental scales, and is caused by both barriers to …
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ENGINEERING PHAGE HOST RANGE PROMISCUITY
… in nature due to their capacity to facilitate horizontal gene transfer. Tailed bacteriophages have been studied intensively, and they rely on tail spikes or tail fibres to recognise their cognate host receptors when adsorbing to bacteria. This adsorption step is crucial for the infection …
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