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Showing 1 to 2 of 2 for “"hnRNP proteins"”.
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Formation of an Exon-Defined A Complex Spliceosome Intermediate Results in CD45 Exon Repression
… the CD45 gene. ESS1 is bound by at least three hnRNP proteins (hnRNP L, PTB, hnRNP E2) of which hnRNP L is the main functional component. Subsequent work showed that ESS1 does not regulate CD45 exon 4 splicing by the typical mechanism of preventing exon definition. Instead, spliceosome assembly …
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Regulation of Human Papillomavirus Type 16 Late L1 mRNA Splicing
… which encode highly immunogenic viral structural proteins are only expressed in the suprabasal layers. HPV-16 infections are normally cleared within 18-24 months, but HPV-16 can establish persistent infections that progress to cancer. Such HPV-infected cancer cells express early HPV-16 genes but …