Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 1 of 1 for “"hit optimization"”.
-
Discovery of macrocyclic inhibitors of challenging protein-protein interactions
… size and diversity towards the discovery of hits against challenging disease targets. In my second project, I have applied these new tools of high-throughput synthesis to prepare a chemical macrocycle library of unprecedented diversity. A design was conceived in which 4-mer peptides would be …