Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"histone crotonylation"”.
-
Insights into the molecular mechanisms of function and regulation of histone crotonylation
Histone posttranslational modifications (HPTMs) are major regulators of chromatin dynamics and gene expression. Knowledge about the molecular machineries involved in the regulation and interpretation of a HPTM is crucial for understanding their functional significance. Histone crotonylation is a …
-
Metabolic Regulation of Gene Expression through Differential Histone Acylation: The Regulation and Function of Histone Crotonylation
<p>Histone lysine acetylation (Kac) plays a critical role in gene regulation by affecting the accessibility of the DNA wrapped around histones and by recruiting effector complexes. Three major classes of proteins are associated with Kac, namely "writers," enzymes that covalently modify specific …