Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"histone H3 methylation"”.
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Investigating histone H3 Lys4 and Lys9 methylation in conditionally immortalized olfactory placode by matrix-assisted laser desorption
… have shown that distinctive site-specific histone H3 methylation patterns at lysine 9 and lysine 4 determine the formation of heterochromatin oreuchromatin, respectively. The biological significance of lysine 4 and lysine 9 methylation of histone N-terrriinal tails was investigated in this …
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An investigation into the significance of histone methylation in various mouse tissue
Histone lysine methylation is a post synthetic modification that occurs on the N-terminal tails of histones H3 and H4. This modification occurs at very specific residues, which have been highly conserved throughout evolution. It has been postulated that histone methylation may be involved in the …
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Methylation Change of Histone H3 and CpG Sites at the TIM-3 Gene Promoter in Response to Stimulation
… DNA 메틸화 변화는 일어나지 않았다. 다음으로 TIM-3 promoter에서의 히스톤 H3 메틸화는 PBA와 A23187 자극에 의한 T 세포를 활성화 시켰을 때 proximal TIM-3 promoter (-954 ~ -34) 부위에서 H3K4me2의 수준이 증가되었고 distal TIM-3 promoter (-1549 ~ -1048) 부위에서 H3K9me3와 H3K27me3의 수준이 증가되었다. 본 연구의 결과는 TIM-3 전사 조절을 이해하는데 중요한 기초로 제공될 것이다.
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HISTONE-DEPENDENT AND HISTONE-INDEPENDENT PATHWAYS FOR RAD9 CHROMATIN RECRUITMENT AND CHECKPOINT ACTIVATION
… Ddc2, the Ddc1 component of the 9-1-1 complex, histone H2A. Another Mec1 target is adaptor Rad9. Phosphorylation of Rad9, followed by its oligomerization, allows the recruitment and activation of the effector checkpoint kinase Rad53. This is a key step in the signal transduction cascade; it can …