Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 26 for “"hippocampal volume"”.
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Sex and seasonal variation in hippocampal volume and neurogenesis in the eastern chipmunk, Tamias striatus
… adult neurogenesis. In wild-living species, HPC volume and neurogenesis have been found to differ between the sexes and vary seasonally in tandem with spatial behaviours such as food-caching and mating. However, few studies have simultaneously compared across sex and season, and the literature …
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A neuroimaging investigation of the association between aerobic fitness, hippocampal volume and memory performance in preadolescent children
… survival in the hippocampus as well as enhanced hippocampal-dependent learning and memory. Recent evidence extends this relationship to elderly humans by suggesting that high aerobic fitness levels in older adults are associated with increased hippocampal volume and superior memory performance. …
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Associations Between and Changes in Hippocampal Volume and the Cortisol Response Over Time: The Role of Childhood Maltreatment and Depression
… HPA axis dysregulation and reductions in hippocampal volume, have long been associated with the pathology of major depressive disorder, especially within the context of a history of childhood maltreatment. However, investigations that examine the association between these two mechanisms …
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Hippocampal Volume and the Detection of Mild Cognitive Impairment in an Older Adult Population: Assessing Performance on Cognitive Screeners Administered In-Person and Electronically
… assessment measures predicted subcortical hippocampal volume and cognitive decline consistent with mild cognitive impairment. It was hypothesized that the Montreal Cognitive Assessment would display better predictive strength than the Cogstate Brief Battery when evaluating subcortical …
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The relationship between elevated night-time Glucocorticoid activity and dreaming: a perspective on sleep-dependent memory consolidation
… episodic memory impairment, and reduced hippocampal volume. This dissertation had two primary aims. The first was to explore the relationship between corticosteroid exposure and sleep-dependent memory processes, including dreaming, with special focus on associations between corticosteroid …
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The neural correlates of intimate partner violence in women
… alcoholism have decreased brain weights and volumes. The hippocampal volume reductions in patients with chronic alcoholism have been found to be proportional to the reduction in total brain volume. Thus alcohol consumption needs to be accounted for in studies examining hippocampal damage. …
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A Glial Role in the Action of Electroconvulsive Therapy
… has in recent years been associated with volumetric changes in prefrontal cortex, hippocampus and amygdala, brain regions known to be implicated in emotional behavior. Post-mortem analysis of brain tissue from depressed patients, have suggested that neuronal and glial pathology, seen both …
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The effect of repetitive head impact exposure on white matter lesion volume
… supporting evidence by comparing the total volume of fluid-attenuated inversion recovery (FLAIR) white matter lesions in individuals with a history of RHI from CCS to those without a history of RHI from the Boston University Alzheimer’s Disease Research Center (BU ADRC). The RHI participants …
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An Analysis Of Virtual Place Learning/navigation In Children And Young Adults Prenatally Exposed To Alcohol
… performance on this task is dependent upon hippocampal function. Rodents prenatally exposed to alcohol are impaired on the Morris water maze and show damage to hippocampal neurons. A human analogue of the Morris water maze, the virtual water maze has been created using computer-generated 3D …
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Sex differences in the actions of psychoactive agents and progesterone on anxiety-related behaviour in the mongolian gerbil (meriones unguiculatus) and the effects of corticosterone on the hippocampal morphology of wistar rats (rattus norvegicus)
… influence of chronic corticosterone treatment on hippocampal volume and astrocyte cell numbers in male and female rats. Pharmacological validation of the elevated plus-maze and blackwhite box revealed that diazepam produced similar anxiolysis in male and female gerbils. Buspirone appeared to …
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Aerobic Exercise and Hippocampal Plasticity in Young Adults with Depression
… between symptom severity, hippocampus volume and N-acetyl-aspartate (NAA) concentration, a marker of neuron density/viability, has been shown. The relationship of these variables to fitness (as assessed by volume of oxygen uptake - VO2 max) is underexplored. In this study, unmedicated, …
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The Cellular and Molecular Determinants of Hippocampus Size in a Female Monkey Model of Depression
… to those mechanisms are unknown. Reduced hippocampal volume is reported in depressed patients, yet the interpretation of human studies is confounded by subject heterogeneity. Although the hippocampus is functionally differentiated such that the anterior hippocampus is associated with …
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The effect of repetitive subconcussive head impacts on observed physiological, biochemical, and functional perturbances in the brain in high school and collegiate football players: a systematic literature review
… medical literature from 2009 to current. Hippocampal volume changes, white matter diffusion changes, neurocognitive and neurophysiological performance, serum brain marker, diffusion-weighted tensor imaging changes, and head impact telemetry were outcomes of interest. Our initial search …
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Memory functioning in children exposed to domestic violence trauma
… in memory associated with reductions in hippocampal volume. However, a question arises as to whether children who have been exposed to domestic violence trauma will differ from controls in their memory functioning. A question also arises as to the relationship between the children's …
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Photoperiod, Brain Plasticity, and Behavior
… reduced brain size, and a marked reduction in hippocampal volume. Given that the hippocampus is critical for spatial learning and memory, I explore the functional outcomes of having a small hippocampus in Chapter 2 utilizing a spatial learning and memory task. I also assess neuronal physiology …
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Iron deficiency affects spatial learning in neonatal piglets
… deficiency on cognition was assessed using a hippocampal-dependent spatial T-maze task. Severely deficient piglets were unable to acquire the task (P = 0.3937), while mildly deficient piglets had lower performance when the reward location was reversed than those on the adequate diet (P = …
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Automated Brain Mapping to Evaluate the Relationship between Neurodegeneration, Cerebral Small Vessel Disease and Structural Covariance Network Disruption in Alzheimer's Disease
… and validates a state-of-the-art automated hippocampal segmentation technique for magnetic resonance imaging to accurately measure neurodegenerative status in mixed disease samples. The second part of this thesis assesses the relationship between hippocampal volume, SVD burden and grey …
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Automated hippocampal location and extraction
… that is able to first locate and then extract hippocampal volumes from 3D 1.5T MRI T1 brain scans automatically. The hybrid algorithm uses brain atlas mappings and fuzzy inference to locate hippocampal areas and create initial hippocampal boundaries. This initial location is used to seed a …
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Subacute Hippocampal Atrophy Following Traumatic Brain Injury: Relationship to Environmental Enrichment and Vocational Outcome
… to severe traumatic brain injury show bilateral hippocampal atrophy progressing beyond the acute stage post-injury. The present study proposes a novel, integrated model of neuroprotection against subacute hippocampal atrophy (i.e., atrophy occurring beyond the initial 3 months post-injury) via …
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Influence of ApoE polymorphism on synaptic morphometry during aging in the dentate gyrus of ApoE knockout and human ApoE transgenic mice
… At 18 months old, hApoE2 mice have a greater hippocampal volume and display the highest syn/nrn and glutamate immunogold labelling in presynaptic boutons and dendrites of the MML, compared to hApoE3 and hApoE4 mice. In AD patients, such effects of the ?2 allele may act as a synaptic …
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