Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"hippocampal subfields"”.
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The contributions of hippocampal subfields to the age- and fitness-dependent effects on cognition
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2027-05-01
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Immunological investigations into synaptic plasticity
… to map time- and locus-specific changes in hippocampal subfields following long-term potentiation in the rat. In the first series of experiments an antiserum (RI4) was raised against protein from chick forebrain postsynaptic densities (PSDs). The antiserum was characterised and was found to …
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Cardiorespiratory fitness as a modulator of hippocampal subfield structure and function in cognitive aging
… paradigms in humans. Age-related impairment in hippocampally-dependent cognition emphasizes the importance of identifying modulators of hippocampal plasticity. Critically, studies in older adults have demonstrated that greater cardiorespiratory fitness (CRF) is associated with greater volume of …
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Medial Temporal Lobe Does Not Tell The Whole Story: Episodic Memory In ‘atypical’ Variants Of Alzheimer’s Disease
… cortex of the MTL, which then spreads to hippocampal subfields, and later to neocortical areas. Cases that are less recognized by the general public are patients with the atypical variants of AD. Interestingly, many of the atypical cases of AD appear to share the same histopathological …
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Quantitative MRI correlates of hippocampal and neocortical pathology in intractable temporal lobe epilepsy
… of quantitative relaxometry and DTI from hippocampal and neocortical specimens of intractable TLE patients. To achieve this goal I developed and evaluated a pipeline for histology to in-vivo MRI image registration, which finds dense spatial correspondence between both modalities. This …
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Pharmacological Intervention Reduces Hippocampal Hyperactivity in a Mouse Model of Psychosis
… of a model in animals putatively parallel to hippocampal hyperactivity in human schizophrenia brain. A reverse-translational mouse model of psychosis has been developed based on subchronic chemogenetic inhibition of dentate gyrus (DG) during adolescence and it could become a candidate for …
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Neural Correlates of Temporal Context Processing
… techniques. The fMRI study investigated whether hippocampal representations in CA1 and DG/CA3 subfields were sensitive to the flow of physical time, and if so, whether the number of events that occur during a time period influences the temporal representation of a target event. Results showed …
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Tracking The Flow of Information Through The Hippocampal Formation In The Rat
… examines the flow of information through the hippocampal formation while attempting to determine the computations that each of the hippocampal subfields performs in learning and memory. The formation, storage, and recall of hippocampal-dependent memories theoretically utilize an …